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According to the St. Louis Fire Department, the fire was reported around 8 p.m. on or about the 24th floor of the building at 200 South Fourth Street.

A St. Louis area dog is a finalist in Purina's Chief Snuggle Officer contest.

It was a chaotic night when what was meant to be a pool party for friends ended with two St. Louis County police officers shooting teenagers in a fast-food restaurant parking lot.

A south St. Louis couple was disheartened after learning two young people yanked an electric sign from their yard and ran off with it. The sign was a well-known fixture in the area for its positive messages.

An effort to remove the King James Version of The Bible from St. Charles County library shelves falls short.

One man was killed and three others were hurt on Tuesday morning in a shooting in Wellston.

The second edition of Missouri’s Cold Case Playing Cards features 52 unsolved cases involving homicides, missing people, and unidentified human remains from across the state.

Cincinnati's Dane Myers dropped a fly ball with two outs in the ninth, opening the flood gates in a six-run inning to give the St. Louis Cardinals a 10-9 win over the Reds.

An elderly woman died from injuries she suffered in a house fire Thursday morning in Granite City, according to the Madison County Coroner's Office.

Banana Ball is back in St. Louis. The Savannah Bananas, who bring a wacky, high-energy twist to baseball, return to Busch Stadium this weekend for the second straight year.

Missouri U.S. Eric Schmitt participated in the BMW Championship's Gardner Heidrick Pro-Am event on Wednesday at Bellerive Country Club. Schmitt spoke with FOX 2's Kevin Ryans after his round of golf to discuss the tournament, plus his efforts to reshape the future of college athletics.

One man was shot Thursday morning in Clayton, Missouri at an intersection near Shaw Park, police say. Two people connected with the shooting are in custody.

Governor JB Pritzker and the Illinois Department of Revenue announced disaster tax relief for people and businesses in 15 counties affected by severe summer 2026 storms.

On Wednesday, officials identified the remains of two people who went unidentified after a 1971 train crash in Salem, Illinois.

Two legendary rock bands will now share the stage in St. Louis next month. The Foo Fighters will join forces with AC/DC for one night only and step in as the supporting act.

WASHINGTON COUNTY, Mo. - A Union man was killed in a single-vehicle crash Wednesday afternoon on Highway 47. According to the Missouri State Highway Patrol (MSHP), the crash occurred around 4:15 p.m. on Highway 47 near Calico Creek Road. It involved a Ford F-150. Police said the crash happened after the Ford traveled off the [...]

The St. Charles County Police Department has discontinued its use of Flock cameras and tightened up access to vehicle-location data after an audit revealed an employee abused the system for a personal purpose.

ST. LOUIS - Police are investigating after a pedestrian was struck and injured in a suspected hit-and-run crash early Thursday in north St. Louis. According to the St. Louis Metropolitan Police Department, officers responded to the 3900 block of Olive Street Thursday morning after reports of a woman lying in the street after sustaining a [...]

MADISON COUNTY, Ill. - All lanes are closed on Illinois Route 255 after a person was killed and others were injured in separate crashes Thursday morning in Edwardsville. According to Illinois State Police, the crash occurred shortly before 5:30 a.m. on northbound and southbound IL-255 at Wagon Wheel Road near Interstate 270. Police said the [...]

One person was injured and a house sustained significant damage after a fire broke out on Avenue H in Mehlville early Thursday morning.