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Arrieon Watson, 24, faces a count of second-degree murder in addition to other charges.

Just before midnight two vehicles collided in the southbound lanes of I-55, just south of Carondelet

“They told us there was nothing to worry about in this site, it was no big deal. Just for once, come out and tell us the truth.”

"We shared a lot of incredible moments together. I’ll remember all of them. And I’ll remember the feeling I had every time I put on the Cardinal jersey: gratitude."

Smith-Schuster wasted little time in announcing the move himself, tweeting to Chiefs fans: "Let's Go!"

"The data that is coming out is showing an increased incidence in younger and younger populations,” said Dr. Melissa Tepe of Affinia Healthcare.

The company that's run Busch Stadium's concession stands for 50 years will host a hiring fair Saturday, March 19.

Police said the man was shot in the arm and abdomen by a lifelong friend during an argument.

Officer Garrett Worley was injured in a shootout with a suspect at a Bonne Terre motel Thursday morning, which left fellow Officer Lane Burns dead.

A 5 On Your Side viewer had a check stolen and wanted to make sure it doesn't happen to others.

For the Fighting Illini, reminders of last year's tournament have only strengthened their resolve to go further.

"I want to give him a hug. That's all I want. I just want to give him a hug and I just want somebody to tell me that he's OK, but he's not."

Happy birthday, Patricia!

The collisions began about 8 a.m. Thursday on Interstate 57 as thick fog enveloped the Charleston area, about 150 miles south of St. Louis.

Officials said the Northside Economic Empowerment Center will be a technical assistance hub to support growth in small businesses in north St. Louis.

"Hamilton" runs April 12 to May 15 at the Fox Theatre. Win with Five at the Fox!

The trial is focused on studying the drug's treatment of relapsed or refractory (R/R) T-cell acute lymphoblastic leukemia (T-ALL)/lymphoblastic lymphoma (LBL).

QuikTrip is asking to rezone a former furniture store from commercial and residential to just commercial, and for a conditional use permit.

The two left lanes of I-44 eastbound near Antire Road were closed for about two-and-a-half hours.

When folks heard Patrolman Burns was shot and killed early Thursday morning and Corporal Garrett Worley was critically wounded while on the job, the news hit hard.