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A think tank looked at five taxation areas: corporate, individual income, sales/excise, property/wealth and unemployment insurance.

A St. Louis-based clinical-stage biotechnology company developing cancer-fighting drugs has hired a new medical chief.

A panel of Missouri appellate judges ruled Tuesday that the constitution’s “plain, unambiguous” language means cities and counties cannot stack marijuana sales taxes. The Missouri Court of Appeals Eastern District’s decision reversed a lower court’s ruling in May that allowed both Florissant and St. Louis County to impose a 3% sales tax on marijuana products. That resulted in customers at the Florissant-based dispensary Robust Missouri 3 LLC paying a total sales tax of 20.988% — a 14.988%…

In the days before Missourians voted to enshrine the right to abortion in the state constitution, incoming House Speaker Jon Patterson declared lawmakers should respect the people’s choice, whatever the outcome. Now, with abortion set to become legal in Missouri, Republican Rep. Justin Sparks of Wildwood is mounting a long-shot challenge seeking to block Patterson from the top leadership position in the Missouri House, arguing that he is not up for the job of defending anti-abortion values. “On…

The Clayton venture capital firm has named its first operating partner, to focus on advising portfolio companies about partnership strategies with larger businesses and growth strategies.

The first St. Louis-area location of a Missouri-wide beer, wine and liquor retailer has set an opening date.

Homebuilders like Jim Brennan’s McKelvey Homes have feasted on St. Charles County’s surge in population over the past 70 years. They still intend to build homes in the county, only now the question becomes: What land is left?

As part of this year's 40 Under 40 Awards program, we asked our honorees to share what their St. Louis happy place is — where they like to spend time whether they do it alone, or with their families, friends, or partners.

In less than two years of selling legal recreational weed, Missouri’s cannabis market has grown to $1.4 billion — outperforming states with a longer history of marijuana legalization like Arizona, Colorado and Nevada. “Those are mature marketplaces, and you are surpassing them,” said Laurie Parfitt, CEO at LKP Impact Consulting. “Missouri is doing amazing things, and we expect tremendous growth in this market going forward.” Parfitt gave a year’s overview of Missouri’s cannabis…

The coalition of St. Louis and Kansas City pro teams that spearheaded a ballot referendum to legalize sports betting in Missouri saw it narrowly pass last week, though with a framework that could drastically diminish the value of the licenses they secured as part of it.

Small businesses are the backbone of local economies. Their success lends itself to stronger communities by creating new jobs, driving local economic growth and offering residents more options and opportunities. We’re in the midst of a booming workforce here in St. Louis, recently named a top 10 metro for job growth for first time since the ’90s, according to new data from the U.S. Department of Labor’s Bureau of Labor. The city has also been one of the fastest growing hubs for innovation and…

Organizers have five days of activities planned across the region for STL Startup week, during which the St. Louis Economic Development Partnership will host open houses at three of its incubators.

There has been a recent copyright ruling that should satisfy dessert lovers everywhere regarding the general availability of the McFlurry, which is an ice-cream-based dessert offered at McDonald’s restaurants. To the uninitiated, the McFlurry has become a bit of a cultural phenomenon in that it is frequently “off the menu” due to the machine used in its preparation being inoperable. It’s such a bizarre intersection of technology, business, corporate policy, public relations and intellectual…

A more than 100-home subdivision could be built along Manchester Road in St. Louis County if it gains approval.

Republican and Democratic lawmakers gathered in Jefferson City this week to choose new leaders for the upcoming legislative session in January. In the Missouri Senate, where GOP infighting has caused unending gridlock for the last few years, Sen. Cindy O’Laughlin was chosen by her caucus to be president pro tem — the highest ranking job in the chamber. O’Laughlin, of Shelbina, is the first woman to ever hold that position in Missouri. She previously served as Senate majority leader. “I…

A new coffee bar is opening in downtown Clayton next month. HiFi by Upshot Coffee is planned to open Dec. 1, at 8401 Maryland Ave. at Crandon Drive, with a Japanese-inspired concept. In a release, the company said the shop will offer "specialty coffee drinks and a thoughtfully curated breakfast and lunch menu in a distinctive Japanese record bar-inspired space complete with a top-notch hi-fi sound system." “My vision for Upshot and HiFi is to create unique, memorable, and welcoming spaces…

A Chicago man has sued the owner of the Railway Exchange Building in downtown St. Louis, alleging he was severely injured while in the property’s parking garage.

A credit union has expanded its offerings by launching an insurance agency through a partnership with a Massachusetts-based company.

Both Missouri Gov. Mike Parson and St. Louis County Executive Sam Page are accepting applications to replace Wesley Bell in the St. Louis County Prosecuting Attorney's office, but it is unclear who will get to name that replacement. Bell won a seat in the U.S. House of Representatives on Tuesday, and on Wednesday, Page announced his office had begun the search for Bell's replacement. On Friday, Parson announced that his office had opened its own search for Bell's replacement, and Missouri Attorney…

A former New York bank executive and regulator is the newest director of a Clayton-based bank.