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St. Louis lawmakers on Tuesday gave final approval to a new 14-ward map, with ward reduction set to kick in after the April 2023 election.

“It’s not a commodity. This is a long-term investment and I’ve always taken that approach," Michael Staenberg, president of The Staenberg Group, said of real estate. "I worry today that a lot of the brokers and investors are thinking that they can just trade it whenever they want."

Electric utility Ameren Missouri said Tuesday it plans to close its coal-fired power plant in Festus earlier than previously planned.

Centene Corp. (NYSE: CNC) would appear to have strong internal and external candidates to replace Chairman and CEO Michael Neidorff, who said Tuesday he's retiring from that role next year.

Pfizer, which has a research and development facility in Chesterfield, said it will acquire a San Diego company that's developing treatments for diseases in gastroenterology, dermatology and cardiology.

Schlafly Highland Square, at 907 Main St. in Highland, is the brewery's fourth location in the St. Louis region.

St. Louis had been the largest U.S. city without a nonstop flight to Europe. Lambert airport's leader said new "regional support" was key to changing that.

The St. Louis proposal, led by economic development group Greater St. Louis Inc., is one of 60 finalists in the U.S. Economic Development Administration’s $1 billion “Build Back Better Regional Challenge.”

Centene Corp. (NYSE: CNC) said Tuesday that its chairman and CEO, Michael Neidorff, plans to retire from his CEO role next year, as it also announced changes to its board and an agreement with an activist investor.

Amazon is planning to rebuild its Edwardsville warehouse that collapsed in a tornado Friday, killing six of the company’s workers.

Other than service to Iceland, the last nonstop flight to Europe from Lambert was American Airlines' October 2003 service to London's Gatwick Airport.

The St. Louis-based real estate company paid $36 million for a suburban mall as the company sought to further expand its retail portfolio in Minneapolis.

After a national search, the private Catholic college prep school chose a candidate already well-known to the school as its next leader.

The government technology integrator, which works with the National Geospatial-Intelligence Agency, has opened a new office in the region.

Federal officials are opening an investigation into the deadly collapse of Amazon’s warehouse in Edwardsville in a tornado Friday, as the e-commerce giant said that the newly built warehouse didn’t appear to have any structural deficiencies that contributed to the disaster.

Amazon said it is providing employees and contract workers with relief supplies and services with transportation, food and clean water, and other immediate-needs support.

Kara and Dave Bailey, owners and operators of the restaurant, renovated the entire front of house, including refinishing the original wood floors, adding new tile and fixtures in the bathrooms, painting and redoing the bar. New equipment was also added to the kitchen.

The German successor to Monsanto, with its crop science headquarters in St. Louis, said it was "encouraged" by the Supreme Court's move Monday, in a case that could "effectively and largely end the U.S. Roundup litigation."

The nonprofit organization awarded $100,000 in funding to the four St. Louis-based startups through its Growth Grants program, which launched earlier this year and is designed to offer follow-on capital to Arch Grants’ portfolio companies.

A fast-growing artificial intelligence software company in the Kansas City area has acquired an IT consulting business based in O'Fallon, Illinois.