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“The year of validation.” That's how one investor has summed up 2021 for St. Louis’ entrepreneurial economy thanks to a year marked with several significant exits, including two of the region's most prominent startups becoming public companies.

"What I like is that this is the highest and best opportunity for me to use a skillset and my God-given talent and apply it in a way that mutually influences and benefits both countries to which I owe a debt of gratitude," said Sonette Magnus, Canada's honorary consul for the St. Louis area and partner at Thompson Coburn.

WASHINGTON (AP) — U.S. health officials’ decision to shorten the recommended COVID-19 isolation and quarantine period from 10 days to five is drawing criticism from some medical experts and could create more …

Rush is set to be immortalized as a pinball machine. A silver ball game dedicated to the Canadian prog legends is about to be released. Manufacturer Stern Pinball will debut…

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Our favorite stories of the past 12 months shine a light on the local artists, makers, designers, and personalities whose work brings creativity and joy to our city.

On the banks of the Mississippi, the small city is home to some architectural marvels.

The cause of the crash is unknown.

Missouri’s two largest counties will continue their efforts to overturn a court ruling that severely limits the powers of local health departments at the same time health officials warn the Omicron variant …

Combing through old newspapers and thinking about the past and present South Jefferson and Gravois area.

A dining critic's reflections on the year that was.

Amid holiday gatherings and a spike in cases, health officials, stores strive to keep up with the demand for in-person and at-home testing.

Auditor says office can’t ensure businesses pay the correct application fees.

English majors have grown to 131 this year after dropping to a low of 99 in 2018.

The events, listed chronologically, were chosen based on ‘their scientific or societal impact to our area.’

Officials have until Feb. 1 to respond with a plan to reopen the tourist trolley by June 1

The proposed Lincoln Land Energy Center near Pawnee would emit more carbon dioxide than 800,000 automobiles every year.