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Three local Chick-fil-A franchisees invested in a PPE distribution business. In a lawsuit, they now compare it to a Ponzi scheme.

The SLU study showed it was possible to stretch the vaccine supply if it was given just under the skin.

The independent said there was no path forward for his bid after controversial ex-Gov. Eric Greitens lost to Attorney General Eric Schmitt on Aug. 2.

Katherine Pinner, a 55-year-old political newcomer from unincorporated St. Louis County near Affton, sued the American Association of Orthodontists claiming religious discrimination.

It’s an effort to broaden the extent of his power in Democratic circles as the state party maintains its total control of Illinois government.

It was the Republican governor’s first public statement about the ballot question since it was certified for the November ballot.

The mayor said in a Tweet Megan Green supports working families, works to protect abortion rights and promotes "equitable development."

CLAYTON — The St. Louis County Council's meeting Tuesday was the first in-person meeting accessible to people using wheelchairs in the more than 50-year history of the county administration building.

Future Civil War general and president found a romance that endured for 36 years.

Norma Walker will replace former alderman Jeffrey Boyd who resigned in June following federal corruption charges.

John Collins-Muhammad's plea agreement puts his possible prison term between three and four years.

Glenn Emerson Cook was the first of three U.S. veterans with no known family laid to rest Tuesday at Jefferson Baracks National Cemetery.

Authorities identified the two construction workers who died after suffocating in a manhole while working at a residential construction site in Edwardsville.

Bridgeton police plan to send overnight detainees to the St. Charles jail.

Party officials will meet Thursday to pick a new nominee.

Jeffrey C. Hunt, 58, of St. Charles, died at the scene.

The Missouri Highway Patrol identified the victim as Trerion T. Harvey, 22, of Warrenton.

Chelsey M. Lawrence, 30, crashed along a curve on Byrnes Mill Road.

Two protests were held Monday at Kickapoo High School in Springfield, where teachers were told last week to remove the pride flags because of a school district policy on employee speech and conduct.

Ian Froeb's STL 100 lists his picks for the top restaurants in St. Louis. Here, we highlight the best places listed to grab a sandwich.