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SSM Health has signed a deal to take over a six-story office building that Centene Corp. vacated as part of its prolific downsizing last year.

Farmers say they can't plant crops or run machinery on parts of their land, pointing to debris and gullies. Spire says it's working "in good faith" to fix problems.

Columnist Bill McClellan writes: We the People often need guidance. That is obvious right now.

The newly appointed dean at WashU's business school, Michael Mazzeo, sat for an interview with the Post-Dispatch to talk about teaching, baseball and the joy of business.

Veteran college counselors aren’t sure how the changes in this cycle will play out in admissions decisions.

Swade dispensaries are tapping into the music festival and outdoor event scene following this year's legalization of adult-use, recreational marijuana.

It’s considering a plan to give McBride Homes 32 acres of Koch Park to build 108 new two-story houses there.

For decades, the Rev. Larry Rice has made a practice out of publicly poking mayors in the eye to bring attention to the plight of people living on the streets.

Skeptical residents of troubled Hillvale Apartments say the repairs fall short — and won’t last, given the problems in the surrounding area.

First Bank's new headquarters, under construction near Olive Boulevard and Interstate 270, will open in April.

The devices could shorten response times when prison guards are under duress.

Nicholas "Sifu" Alsup, 30, hopes to outwit, outplay and outlast the competition to win $1 million.

Thomas Sanderson has sued over a requirement that sex offenders post a sign on their house for Halloween. He says it violates his First Amendment rights.

“We’re still pursuing that, but we wanted to make sure we can staff up first,” Mayor Tishaura O. Jones said.

One person was killed and another two were injured Sunday night in a crash on the board of the city's Dutchtown neighborhood.

The cyberattack early Saturday had left the agency unable to contact customers or access the scheduling system, leaving riders waiting for vans that never came.

Never get in a headline battle with Larry Rice if you're the mayor. It won't end well. There's a better way.

St. Louis will get 99% of a total eclipse. The full effect can be seen in Ste. Genevieve, Mo., or Nashville, Illinois.

The closure, starting at 9 a.m. Monday, is needed to allow bridge rehab work.