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A car hit an Illinois state police vehicle Saturday night in Granite City, injuring the state trooper.

Americans spend more than $420 billion per year at pharmacies for prescription drugs, according to a 2022 report from the Department of Health and Human Services.

Officials in Silex have declared an emergency from high radium levels in the public water supply, and are offering bottled water to residents as an alternative.

The suspect gunman was hospitalized in critical condition after the shooting shortly before 10 a.m. in the 3800 block of Shenandoah Avenue. No police officers were hurt.

Stephen Jacbosmeyer was once the St. Louis police's golden boy, then everything crumbled, then he rebuilt it.

Attempts at book banning are rising and more successful — especially in school libraries — than ever.

“When we talk about how we handle people in poverty, those are usually our hardest conversations,” said Alderwoman Alisha Sonnier.

Without federal intervention, states are left to wrestle with the complex question of how to respond to such mergers.

Sen. Eric Schmitt and Reps. Mary Miller and Mike Bost voted against the continuing resolution.

Midwest BankCentre has supported female-led startups for over 20 years. St. Louis leads the country in these efforts, according to database PitchBook.

The west half of the SILO stadium plans include two lighted, artificial turf fields for soccer, lacrosse, field hockey softball or baseball

Both a male and female victim were found dead inside a south St. Louis home Saturday, in an incident that police have categorized as a homicide.

Five people were killed and five were critically injured when a semitruck carrying anhydrous ammonia crashed in central Illinois about 110 miles northeast of St. Louis.

Max Jones, of Hazelwood, faces one count of murder in the 2nd degree and one count of armed criminal in connection with the fatal shooting of a man Friday in Ferguson.

Is our economy doing better or worse? See recent changes in local employment, regional inflation and more in these regularly updated charts and maps.

Willie Crowder, 40, of Pine Lawn, was caught on video footage fatally shooting Dominic Harris in the 3000 block of Gary Drive, in Velda Village Hills, according to court documents.

The Opportunity Trust will open or expand 16 charter schools across Missouri in the next five years.

High school students, top police officials and community advocates gathered to hear from a nationally known criminal justice professor on ways to address the rift between Black people and police.

A Jennings teen was charged Friday with having role in a burglary where a pickup truck was rammed through the front of a north St. Louis County dispensary.