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Four lawsuits filed since mid-July argue that the state has intruded on interstate commerce and violated federal property rights protections.

Only 1 in 5 cancer patients respond well to immunotherapy — a treatment that encourages patients’ own immune systems to attack tumors.

Police said the unidentified man was found about 11:30 p.m. near Cora and Evans avenues.

Donald G. Winter, 59, of West Alton, was driving a van that crashed at about 3:25 p.m. Monday.

Planned Parenthood’s chapters in Missouri said Monday they are suing state officials after the health care provider was booted from the state’s Medicaid program.

The appeals court found the Missouri law violated a section of the U.S. Constitution known as the supremacy clause, which asserts that federal law takes precedence over state laws.

The injury comes as city leaders work to invest millions into traffic calming infrastructure.

Three years ago, Cherokee Street businesses voted to evict a controversial Native American statue. Replacements are cropping up down the street.

Protecting your interests requires you to be proactive in preventing litigation.

The St. Louis area faces dangerous heat and humidity this week, with highs set to either reach or fall just shy of 100 degrees through Thursday.

Myers is at least the sixth St. Louis-area superintendent to depart from their role in the past four months.

A favorite part of vacations is eating all the food. On Daniel Neman's trip to the beach, he was the one who was eaten.

St. Louis county police officers responded to a call for service for a person struck around 10:30 p.m. Friday, near the intersection of Meramec Station Road and Crescent Avenue.

A month ago, organizers were promoting the event at a press conference with Mayor Tishaura O. Jones and Greater St. Louis Inc. CEO Jason Hall.

Officers responded to a call around 1:20 a.m. on Saturday for a man slumped behind the wheel at Tucker Boulevard and Convention Plaza.

The St. Louis Preservation Board will review the project Monday.

Mansion House, at 1128 Washington Avenue, will get a multimillion-dollar renovation that would put almost 500 units on the market.

The district hired at least nine administrators connected to the superintendent, Keisha Scarlett. They received a total of $1.6 million in salaries.

Among the improvements are new lighting and marquee, entryway and main floor, new central staircase and new lobby and bar area.

What happens to Cheesecake Factory, the Dillard's store and the Teslas? And what's replacing them? We have answers.