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Republican U.S. Rep. Vicky Hartzler is attempting to distinguish herself in a crowded field of candidates vying to replace U.S. Sen. Roy Blunt.

Ex-St. Louis health director on forced leave several months reaches settlement, but details aren’t released, nor are the reasons for the action.

A man accused of killing four people in the St. Louis area and two more in Kansas City, Kansas, was charged this week in another homicide.

Police on Friday released the name of a man who died after being shot outside of a home in Jennings on Thursday night.

Hiring lifeguards has been like swimming against the current across St. Louis this year.

St. Louis streets officials say a concentrated effort last week reduced the city's big backlog of potholes. Meanwhile, St. Charles County's executive is proposing a $20 million plan to tackle potholes and other pressing road maintenance needs.

A teenager arrested at the scene of a crash that killed five family members has been charged with multiple counts of murder, court officials say.

Searchers continued to comb a popular Wildwood recreation area Friday in their hunt for a missing 72-year-old hiker.

Dave Schatz, the outgoing president of the Missouri Senate, is betting the ad buy will lift him at the right time in the GOP primary.

Pitts Chapel, Springfield’s oldest historically Black church, was founded in 1847 by a group of enslaved Africans.

The masks have been deemed surplus because they expired last month

Columnist Aisha Sultan writes: Why should a disturbed 18 year-old be able to buy two AR-15 rifles and 375 rounds of ammunition — enough to wipe out an entire school?

Two Democrats remain in the race to represent the 2nd Congressional District.

Mehlville High School on Friday switched to virtual learning for its last day of the year after a student received an anonymous threat.

The movie "Star Wars" was released on May 25, 1977, and Joe Pollack reviewed it for the Post-Dispatch that same week.

Police are investigating after a man sitting outside with a group of people in Jennings was fatally wounded in a drive-by shooting Thursday night.

Four workers at the Ferguson and Florissant license offices have been accused of processing vehicle registrations without proper documentation, authorities say.

City officials are targeting summer crime in the downtown area with a combination of increased law enforcement and a variety of summer youth programs.

A St. Charles County judge has ordered a former Dent County sheriff's deputy to serve the rest of his life in prison for a 2011 murder.

Area pastors urge elected officials, including Missouri’s governor and senators, to support universal background checks, other gun control measures in wake of Texas school shooting.