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Five inmates on Tuesday evening escaped the St. Francois County Detention Center and remained at large Wednesday morning, according to authorities.

It’s the first known federal lawsuit filed against the ban.

Three of Linda Morice's close relatives died of cancer in Florissant near Coldwater Creek. Now she is the author of "Nuked: Echoes of the Hiroshima Bomb in St. Louis."

Wildwood Mayor Jim Bowlin, a Republican, will face Rep. David Gregory, R-Sunset Hills, in the 2024 Republican primary for the 15th Senate District, where Sen. Andrew Koenig, R-Manchester, is term-limited.

Ask the experts from the Missouri Department of Transportation, St. Louis and St. Charles counties and St. Louis City your questions about highways and roads. The live chat starts at 1 p.m. on Wednesday.

Brett M. Kress, 26, faces charges of involuntary manslaughter and armed criminal action after police say he fired his gun while chasing Jesse Lopez.

A 3-year-old boy was shot in the back by another child Tuesday afternoon in the city’s Walnut Park East neighborhood.

The proposal has taken on new significance now that nearly all abortions are outlawed in Missouri after the U.S. Supreme Court overturned Roe v. Wade

Manchester officials urged the St. Louis County Council to put off a move that could block the city's efforts to annex a portion of unincorporated county.

Clancy seemed less worried about who was named to the positions, as long as it wasn’t Rita Heard Days, D-1st District, or Mark Harder, R-7th District.

Officers on Tuesday night shot and killed a man fleeing a traffic stop, according to authorities.

Federal programs are tied to an archaic definition of poverty. Just ask the folks at St. Louis area food pantries how that affects their lives.

Vivek Malek is the first person of color to serve in a statewide office in Missouri.

Ferguson-based Emerson is making a play to buy a Texan company, despite rebuffs from its leadership, in a $7.6 billion deal.

The woman fired at least one shot from inside her van outside of the city's Social Security Administration building in Downtown.

Sen. Bill Eigel, R-Weldon Spring, has long targeted the tax.

Brian R. Kelly, 26, was charged in St. Louis Circuit Court with two counts of second-degree murder, two counts of involuntary manslaughter and one count of tampering with a motor vehicle.

Police on Tuesday announced they've arrested a man they believe shot and killed another man who was breaking into his car at a gas station in Soulard.

The same company that operated a St. Louis County program will oversee the statewide program

A local real estate company is proposing to turn two mid-rise apartment buildings in Clayton's leafy DeMun neighborhood into a boutique hotel.