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Laci A Meyer, 28, of De Soto and Rodney D Sharp, 63, of St. Louis were pronounced dead at the scene of the crash just after 1 a.m. in an eastbound lane of I-70 near St. Charles Rock Road.

The company that was sued said the litigation was an attempt to smear its reputation.

Missouri's junior senator is blocking appointments to the Department of Defense, making the country weaker.

Amid a controversy over spending, the Robertson Fire Protection District said they were slashing residential tax rates.

Authorities on Friday identified the man whose body was found in the Big River near Old Byrnesville Road on April 2.

Two men have been indicted on federal drug and gun charges in connection with the fatal shooting of a man in Maplewood in February.

Justin Coffman pleaded guilty in the 2020 shooting death of his brother-in-law Mark Shepard.

Several St. Charles County Officials expressed opposition Friday to a state bill they say would “defund” the county’s public services.

Ohio-based Cornerstone Properties wants to build 256 apartments atop a Planet Fitness in Brentwood.

A St. Louis aldermanic panel will hold a “town hall” meeting Saturday morning at the O’Fallon Park Recreation Complex to get public input on spending the city’s second-year $249 million in federal American Rescue Plan Act money.

ST. LOUIS COUNTY — Interstate 44 near Big Bend Boulevard will close for the weekend in both directions beginning Friday night for removal of the Big Bend bridge.

St. Louis County Police are investigating after a 38-year-old man was shot and died Thursday afternoon in Moline Acres.

To qualify for bonus reimbursement, Illinois nursing homes would have to meet at least 70% of federal staffing level guidelines, and would get paid based on their quality star rating by the U.S. Centers for Medicare & Medicaid Services.

New editor chosen for the St. Louis Post-Dispatch and STLtoday.

Scott Russell Granden of St. Peters groped an emergency room nurse on a flight to Atlanta, prosecutors said. He has been sentenced to 21 months in prison.

Police presence will increase around downtown St. Louis on Saturdays and Sundays through the summer.

The shooting left the victim critically injured on a parking lot. The station is where a security guard was shot and killed in January 2021.

Police said it's unclear where in the city Charles Given had been shot.

O'Neill becomes first Cardinal hitter since 1928 with five RBIs on opening day, while Wainwright pitches six scoreless for 100th win at Busch III.

While many U.S. states and schools have since stopped requiring mask-wearing for COVID, disease experts say children will still need high-quality masks for everything from current and future pandemics to seasonal flu and respiratory syncytial virus that can cause serious…