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With a bad initial message and ice on roads weeks after a snowstorm, Mayor Tishaura Jones' grip on her office seems to be slipping.

Even as a move to regulate pharmacy benefit managers like Express Scripts gets bipartisan support in Congress, a Missouri effort faces an uphill battle in part due to intense pressure from industry lobbyists.

A breakfast and lunch spot in downtown St. Louis has closed — citing the effects of "violence in downtown St. Louis."

Target Corp., which has been among the most high-profile supporters of diversity initiatives in recent years, is now the latest big business to cut back on those policies.

Aldi is opening a new St. Louis-area store in Olivette.

Don Clayton, the CEO of St. Charles-based transportation equipment leasing company Milestone Equipment Holdings, died Tuesday after experiencing a sudden medical emergency, according to the company.

The estimated price for cleaning up leftover radioactive waste along Coldwater Creek in neighborhoods around Hazelwood already stands at an estimated $400 million. But that figure could balloon dramatically as more land is eyed.

A month ahead of the new Major League Soccer season, St. Louis City SC has updated its exterior to reflect the stadium's new name. Here's a look.

Guidelines affect new openings — and even some where people had accepted jobs but not yet started them.

The Missouri state budget will be tighter in coming years as the state finishes spending federal aid distributed for recovery from the COVID pandemic, but Gov. Mike Kehoe said Thursday he remains committed to his promise to end the state income tax. Speaking to editors and publishers attending the Missouri Press Association Day at the Capitol, Kehoe said one of his priorities for cutting taxes this year is to exempt capital gains — the profits from sale of investments like a business or stocks.…

Perhaps you watched the presidential inauguration on television… maybe you did not. To me, this is one of the glorious days of life every four years.

A proposed children's behavioral hospital that had drawn both support and opposition over a series of public hearings got final approval Wednesday night.

A health insurance company has significantly downsized space in its longtime St. Louis-area office, and the landlord is now marketing the building as a multi-tenant space.

Four businesses plan to expand with their share of over $18 million in federal tax credits.

St. Louis aldermen on Thursday amended the compromise legislation for the Rams settlement funds, taking $14 million for downtown and steering it to other priorities.

MediBeacon Inc., a St. Louis-based medical technology company, has received approval from federal regulators for use of its technology in kidney patients.

The Clayton public firm led by Dave Peacock has created a new C-suite position.

Arguably the biggest opponent of unregulated intoxicating hemp products said it’s willing to concede to allowing hemp-THC drinks to continue to be sold in grocery and liquor stores. “We are working through and very excited about the possibility of developing a carve out for low-THC hemp drinks,” said Tom Robbins, a lobbyist for the Missouri Cannabis Trade Association during a Senate committee hearing Wednesday. The legislative battle to regulate intoxicating hemp products kicked off Wednesday…

Bayer pleaded with Missouri lawmakers Thursday to pass legislation critics say would shield the company from lawsuits claiming its glyphosate-based herbicide Roundup causes cancer. Representatives for Bayer argue the legislation would clarify labeling requirements and prevent courts from creating a patchwork of obligations for the manufacturer.  But environmental groups and attorneys for Roundup users who have become ill say the legislation would insulate the company from accountability and…

Panera Bread, the St. Louis-based fast-casual restaurant chain, has named a new development chief to oversee its real estate and franchise growth.