BizJournal 💲📰

The Cortex-based biotechnology startup, which has raised more than $200 million from venture investors, has dosed the first patient in a clinical trial for one of its cancer-fighting drugs. The milestone marks the second drug developed by the company to begin clinical trials.

The St. Louis Business Journal has extended the nomination deadline for its 2022 Business of Pride Awards program, which seeks to recognize and celebrate outstanding LGBTQIA+ business leaders and companies who are advocating for inclusion and equality. Submit your nomination before the new March 25 deadline by clicking here. In addition to celebrating members of the LGBTQIA+ community, the Business Journal again hopes to recognize those who are allies leading their teams with an inclusive lens…

When Emily Hemingway moved to St. Louis about a year ago, she didn’t know much about the region. However, in the months that have followed, she’s made herself a recognizable face in St. Louis technology and entrepreneurship communities.

St. Charles officials say a long-planned — but now imminent — massive project at its riverfront will create new regional "landmarks," drawing in even more residents — and maybe even a corporate headquarters.

"We’ve had a place to hang a hat for the last year and have not really aggressively grown that office until now," the group's president said.

The St. Louis Cardinals announced some changes to the 2022 season schedule Wednesday afternoon, including a three-day extension of the regular season. The changes reschedule five Cardinals away games, but the team’s home opener against the Pittsburgh Pirates on April 7, remains unchanged. First pitch will be 3:15 p.m. The five rescheduled road games were originally planned for March 31-April 6. The final day of the season is now scheduled for Oct. 5. "The Cardinals originally scheduled three-game…

The 75,000-square-foot speculative development is designed to accommodate a range of tenants, including those interested in occupying the entire space to those who only want 5,000 square feet.

A St. Louis-based investment firm has committed to fund $1 billion in renewable energy projects around the country over the next three years.

As the plant-based foods startup seeks to expand its product line and distribution, it’s also expanding its footprint. It has established its own headquarters, taking over a facility formerly used by a shuttered restaurant.

Restaurants and chefs in the St. Louis region have not advanced to the next round of the James Beard Awards, the culinary world’s most coveted prize.

The Clayton-based law firm has been adding offices. It now has 16.

The project, targeted for completion in 2025, will reduce capacity by about 500 seats but add features to improve comfort, such as new, bigger seats, as well as accessibility, including added accessible seating, handrails and three elevators.

St. Louis' lawyers in the Rams litigation were entitled to expense reimbursement, in addition to 35% of any winnings. And they've collected, a document shows.

Boeing in January reported a net loss in 2021 of $4.3 billion, but its top leaders still took home millions in compensation for their work last year.

The Marathon pipeline that ruptured Friday was repaired and is back in operation. The oil company reports roughly 163,800 gallons of oil were released into the Cahokia diversion channel. Emergency crews recovered 465,150 gallons of water and oil mixture. Marathon Petroleum is coordinating response efforts and they reported that several animals have died, but some have survived and are in treatment. Treehouse Wildlife in Dow, Illinois, is caring for the animals injured by the oil spill. When Edwardsville…

The company behind former St. Louis music festival LouFest has agreed to pay a vendor $95,000 in a case tied to the festival's cancellation in 2018.

Memphis, Tennessee-based Development Services Group purchased the 735,000-square-foot, long-vacant building for $6 million in late 2020, planning to transform it into a mixed-use complex.

The commercial real estate market — like virtually every industry — continues to feel the effects of Covid-19. Even as some mitigation efforts ease, the business closures, stay-at-home mandates and social distancing measures have had a lasting impact on people personally and professionally. In the real estate world, these changes created an unprecedented level of volatility as developers, property owners and tenants adjusted to a new way of doing things. “The pandemic was a lot different…

The more than a century-old company is proposing a move to more modern space in St. Louis County where it would relocate roughly 30 employees.

The CEO of a large St. Louis grocery chain, Schnucks, argues that Missouri must invest more in public transit "strengthen our workforce." "The state cannot expect to grow if it fails to invest in its citizens’ ability to access quality jobs, health care, education and other services," he writes.