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A local health care system has purchased the former headquarters of Panera Bread.

Town and Country-based digital consultancy Perficient Inc. has inked a sponsorship agreement with a professional golfer, saying the deal will help boost its international exposure.

Missouri House members on Wednesday took a step toward prohibiting exports of water, arguing the state’s “most precious resource” should be protected and reserved for residents. The bill, which prohibits water exports without a state permit, cleared an initial Missouri House vote 115-25. It needs second approval before it moves to the Missouri Senate, where a similar bill has passed a committee vote and awaits action by senators. Speaking in favor of the bill, Bridget Walsh Moore, a Democrat…

Attendance for Tuesday's St. Louis Cardinals game at Busch Stadium represented a record low for a night game at the venue since it opened in 2006.

The move expands its geographic footprint for the first time in nearly three years.

Social Bar and Grill has closed its south St. Louis County location.

The federal government will spend $3.1 million to reconstruct a "failing parking lot" at a federal building in Overland, an agency said Wednesday.

A metal smelting company based in Korea has acquired a locally-based scrap metal firm through its U.S. subsidiary.

Illinois launched a $14 million New Stores in Food Deserts Program Tuesday to encourage new development of grocery stores in food desert areas.

A bill that would make Planned Parenthood ineligible to receive reimbursements from the state’s Medicaid program passed out of the Missouri Senate early Wednesday morning after an 11-hour Democratic filibuster. The bill now returns to the House, where it can be sent to Gov. Mike Parson to sign into law. This legislation, originally filed by Republican state Rep. Cody Smith of Carthage, is nearly identical to a bill filed by state Sen. Mary Elizabeth Coleman, a Republican from Arnold, which was…

The company behind Fruity Pebbles, Honey-Comb and Honey Bunches of Oats is entering the Dallas metro area after making what could be the largest industrial deal in the region so far this year.

Laumeier Sculpture Park in south St. Louis County said it has laid off seven staff members as funding has decreased.

Centene said in a statement that Meridian has 27 years of experience “developing and maintaining a Medicaid network in Michigan.”

The chairman, founder and CEO of a Clayton-based firm has added to the more than $30 million in shares he’s purchased in the past two years.

WASHINGTON — Republican Sen. Josh Hawley of Missouri thinks he’s found a path for stalled tax legislation that would temporarily expand the child tax credit and restore business tax breaks that are expired or have sunset under the 2017 tax law. Hawley’s idea is to attach the Radiation Exposure Compensation Act to the tax bill to entice his party colleagues to pass it through the upper chamber — including top tax writer and radiation compensation champion Sen. Mike Crapo of Idaho. The House…

Missouri Attorney General Andrew Bailey is seeking to squash a nearly eight-month-old program that has waived $1.2 billion in student loans for 153,000 borrowers and limited the payment amounts for 8 million others.  He is joined by the attorneys general from Arkansas, Florida, Georgia, North Dakota, Ohio and Oklahoma in a lawsuit filed Tuesday in the United States District Court for the Eastern District of Missouri challenging the U.S. Department of Education’s SAVE Plan, an income-driven…

St. Louis has been chosen to participate in the 2024 Startup World Cup, a global contest awarding $1 million to its winner.

St. Louis County Executive Sam Page wants the government to approve a nearly $100,000 contract with political operative Mike Kelley's firm, meant to "inform" voters about a bond issue that could be on the November ballot to replace the Roos government building in Clayton.

Donna “DeDe” DeWitt Lambert, a member of the Cardinals ownership group and sister to club Chairman and CEO Bill DeWitt Jr., died April 6.

The company intends to tear down an existing structure to build a new two-story building, while also looking for new locations across the region to open branches.