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The attack happened Sunday afternoon on a MetroLink train.

Washington University has joined up with a New York investment firm to launch a new drug research and development business, the school said Tuesday.

A St. Louis man is accused of killing another man and then trying to burn down the man's house in north St. Louis County.

"It's freezing out here. This is terrible. I wouldn't wish this on no one."

Ashcroft, a candidate for governor, hired the firm rather than leave the case in the hands of Attorney General Andrew Bailey’s office, where most cases against the state are handled.

State Sen. Karla May said she is alarmed by allegations surrounding the death of vice president Antoinette Bonnie Candia-Bailey.

Missouri’s GOP U.S. senators, Josh Hawley and Eric Schmitt, take to social media to congratulate former President Donald Trump’s win in the Iowa caucuses.

Samuel Butler, 44, died Jan. 11 in the 3600 block of Cass Avenue.

Money and work has been delayed as residents combat raw sewage in yards, homes. The problem has gutted property values, created potential health hazards.

Among the notable renovations are the old St. Charles post office, the former city hall building, the former International Order of Odd Fellows Hall and the former Elks Hall.

On Jan. 16, 1919, the Prohibition amendment was passed, making St. Louis and all cities officially dry despite widespread flouting of the law. Gangs like Egan's Rats, Hogan's and the Cuckoos battled to satisfy the public thirst in St. Louis…

The region didn't break any record low temperatures Monday, but the windchill persisted, pushing temperatures to subzero levels and creating life-threatening conditions.

The U.S. spy agency headquartered in St. Louis is launching a contest to use data to forecast illegal fishing boat traffic in waters across the world.

Trivers is leaving its longtime home near the Gateway Arch to Downtown West.

"We're hopeful that it means the end of probably the worst nuisance property in the city of St. Louis," said attorney Paul Puricelli, who represents residents.

The trial of Thomas Kinworthy, charged with killing one St. Louis police officer and wounding another in Tower Grove South home, is set to begin Tuesday.

At 9:45 a.m. on Jan. 16, 1954, the area's new air-raid sirens began wailing for three harrowing minutes. It was the dreaded "red alert," the warning that a Soviet air attack was imminent.

Lynn is the last remaining guy playoff participant from the 2011 World Series champions, the last Cardinals team to win the title. A rookie in 2011, Lynn also played on the 2013 team that won the pennant (and lost to…

A woman on Sunday evening was shot and killed in a liquor store in Jennings.