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The 154-year-old South City Hospital, formerly known as St. Alexius, said it will start the process of closing the hospital on Friday.

Henry H. Simmons pleaded guilty to a role in the July 4, 2022 death of 32-year-old Bryant Jones.

Kirby R. King was sentenced for involuntary manslaughter in the 1987 death of 22-year-old Karla Jane Delcour.

Hailey G. Zenk, 18, of Winfield, is accused of driving while drunk and high before crashing into a tree, killing three of her passengers.

Southwest Airlines will resume the daily flights to San Francisco next March. The airline already has nonstops to Oakland and San Jose in the same area.

Politics, religion, guns and unfailing loyalty to Trump. It all reminds me of a morals class I took in college.

“If you can land that project and get it here in Missouri ... it’s a big deal for our state,” Gov. Mike Parson said.

As New York, Los Angeles, Atlanta, New Orleans and other cities celebrate 50 years of hip-hop, St. Louis has its own history worthy of recognition.

$50 million will be spend to add lights and safety gates at 27 unprotected road crossings on three Amtrak routes in Missouri.

Cory Henry, formerly of Snarky Puppy, is showing new sides of himself with his “Live at the Piano” album and a tour.

Anheuers-Busch sales are up everywhere, except in the U.S, company leadership told investors during Thursday’s second quarter earnings call.

Officials urged Congress to pass a measure that would expand an existing nuclear radiation exposure survivor compensation program to include St. Louis-area residents.

Fred Heitert, a St. Louis alderman for 32 years and the last Republican to hold an elected office in the city, died Sunday of an illness at his home.

Daniel Donnelly Jr. is facing five federal charges, including impeding or disrupting official government functions and obstructing the U.S. Capitol.

Yitzchak Simon, who worked for St. Patrick Center, filed a federal lawsuit this week seeking damages.

The 8-page letter from Deputy Personnel Director Bryan Boeckelmann alleges rules violations in the high-profile and politically sensitive job searches.

A man on Wednesday evening died after he was shot several times in the city's Jeff-Vander-Lou neighborhood.

The Saint Louis area can expect a hot day. It looks like it will be a balmy 86 degrees. 74 degrees is today's low. Partly cloudy skies are in the forecast. Keep an eye on the radar before you head…

Federal investigators said a dump truck driver in rural Missouri last year may have never seen an oncoming Amtrak train before it was too late.

Dozens of Illinois state employees across multiple agencies are under investigation by a state watchdog for claims they fraudulently obtained payments from a federal pandemic-era loan program.