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With the legalization of recreational marijuana in both Missouri and Illinois, and in many other states across the U.S., doctors want to warn about the impact of smoking marijuana.

License plate reader cameras are tied to many recent remarkable breakthroughs in cases.

There are several global icons that we all know by just one name: Adele, Beyoncé, Cher, Madonna, and Prince. Perhaps the most iconic one is Messi.

A landmark in Soulard, the historic Church of God, is now a total loss after a fire Tuesday night gutted the building.

Lincoln County Sheriff's Office detectives investigated skeletal remains found in an abandoned home in Winfield Wednesday.

Current and former employees of the St. Louis Kitchen gathered Wednesday in the parking lot where their boss was shot and killed on May 30.

In the event of a natural disaster, St. Louis and surrounding areas are preparing through a natural disaster simulation, mimicking mass casualties and responses.

It is time once again for the St. Jude Dream Home Giveaway.

Caught in the act. Three juvenile suspects are in custody, accused of breaking into an O’Fallon, Missouri, residence and stealing the homeowner’s weapon.

A woman thrown off the stage during a rapper's St. Louis County show in 2019 has filed a lawsuit over injuries she suffered.

A Missouri judge is weighing whether to break up a spat between two Republican officials over whether a proposed abortion rights amendment would cost the state billions of dollars in lost revenue from people who otherwise would be born.

A major water main break on Interstate 64 and subsequent severe flooding last month in were something of a wake-up call for Wentzville city leadership.

One man is in custody following a shooting early Thursday morning at a home in rural southern Illinois.

Wildfires in Canada have caused poor air quality and smoky skies across several U.S. metros for several days.

Police are asking for the public’s assistance with identifying a man accused in a murder investigation from earlier this year on Chippewa Street.

A infant is dead and two others injured after a crash in Webster County.

The famous tune Home on the Range starts, "Oh give me a home, where the buffalo roam." It's a message oddly similar to one piece of paper circulating around Missouri mailboxes.

TLC and Shaggy have announced that they will team up for the TLC & Shaggy: Hot Summer Nights Tour 2023, which will bring their biggest hits from the last 30 years.

An aldermanic committee is weighing a possible honorary name change for a street outside CityPark in downtown St. Louis.

USA Today is running a poll to find out what its readers think is the best choice for 2023.