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Officials have issued an Endangered Person Advisory for a 21-year-old woman last seen in the University City area.

From ServMO/Americorps to LaLa Speaks Foundation, two community service events dubbed “Building Bridges of Service” are taking place over the Martin Luther King Jr. holiday weekend.

ST. LOUIS (AP) — Kellen Thames’ 16 points off of the bench helped Saint Louis to a 78-56 victory against Fordham on Wednesday to extend its win streak to 10 games. Thames also had five rebounds for the Billikens (16-1, 4-0 Atlantic 10 Conference). Quentin Jones scored 13 points, going 4 of 7 from the [...]

Residents are voicing their concerns after multiple reported incidents involving tractor-trailers along a stretch of Interstate 70 in Wentzville.

In January of 2025, Brittany Shine asked for prayers because her husband, Wentzville Fire Captain Tommy Shine, was not expected to survive complications from heart surgery. 

The cuts significantly threaten vital overdose prevention services in Missouri, which have contributed to a 26% decline in overdose deaths between 2023 and 2024.

NewsNation sources say the wounded male is in the United States illegally and was a target of ICE's operation.

Millstadt Mayor Michael Todd says village officials are working with the Illinois EPA to establish a temporary solution to ensure continued wastewater treatment services.

St. Louis County Police say a hit-and-run driver is on the run tonight after striking a 9-year-old boy, leaving him seriously injured.

Missouri Governor Mike Kehoe signaled his support for legislation that would enact new oversight for the Missouri State High School Activities Association (MSHSAA).

After more than a decade of twists, the infamous Pam Hupp is finally approaching a murder trial that the judge said should start with a firm Aug. 3 date.

The St. Louis Tornado Recovery Advisory Committee held its third meeting on Wednesday, as city leaders outlined obstacles and progress in the city's long-term tornado recovery efforts.

Law enforcement officials say they have uncovered thousands of files of child sexual abuse material after searching the Moscow Mills home of a former St. Charles County Ambulance District employee.

Stan Kroenke, the Los Angeles Rams owner still viewed by many in St. Louis as a villain for the team's relocation, is now the largest private landowner in the United States, according to a new report.

A woman who helped scammers posing as law enforcement officers has been sentenced in connection with a multi-state spoofing scheme, though which one victim in Jefferson County lost $12,000.

A motorcyclist died from injuries in a crash Tuesday afternoon in Warren County, according to the Missouri State Highway Patrol.

One person was killed and another person was hurt in a shooting Wednesday in north St. Louis.

A Missouri lawmaker has filed a proposed amendment to the state's constitution that would repeal current marijuana laws and replace them with one of the least restrictive systems in the country, getting rid of possession limits, expanding home growing rights, and adding additional protections.

ST. LOUIS - Lona’s Lil Eats creates fresh healthy food fusing Asian soul-food from Lona`s hill tribe village in China, and all the places she`s worked and lived, including right here in Saint Louis. The 2019 James Beard semi-finalist is the home of the Giant Rice Paper Wrap. They make all of their seasonings and [...]

Walmart's drone delivery service is coming to the St. Louis area.