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A 65-year-old woman was killed in a single-vehicle crash in St. Louis after suffering a medical emergency while driving.

The United States will take on Venezuela in the 2026 World Baseball Classic Championship, and FOX 2 will carry the game broadcast. First pitch is set for 7 p.m. CT Tuesday.

ST. LOUIS - Each month on FOX 2, we salute local first responders, military, or veterans with our Proud to Serve award.  This month, we shine the spotlight on Andrew Godi who serves his community of Desoto, MO as an SRO in the Desoto School District.  Sean was nominated by his wife who tells us My husband is [...]

FRANKLIN COUNTY, Mo. - A St. Clair man was reported missing Monday night in Franklin County. According to the Franklin County Sheriff's Office, Robby Miller, 45, was reported missing around 11 p.m. Friday night in St. Clair. Miller is described as a white man standing at 5 feet 10 inches, weighs 180 pounds, and has [...]

A teenager was arrested for spraying pepper spray into a crowd of students at Hazelwood West High School, affecting about 40 students and resulting in one student being transported by ambulance for further evaluation.

ST. LOUIS - It's been a difficult last couple of days adjusting to the cold. We've got one more cold day ahead of us before a better warming trend takes place. Temperatures are dipping into the teens Tuesday morning as skies have cleared. Something to note, we will only be a few degrees shy of [...]

A person was killed in a small plane crash at Spirit of St. Louis Airport in Chesterfield, and an investigation is ongoing.

For Coach Jorge Flores, soccer practice with youth team Dream Big isn’t just about drills, goals, or keeping score. It’s about opportunity.

The new billboard, located along I-55/70 in East St. Louis, is part of an effort to reduce sex buying and trafficking.

Temperatures are forecast to drop into the teens tonight, prompting St. Louis shelters to expand capacity while organizers prepare for Tuesday's St. Patrick's Day Parade in Dogtown.

Police in St. Louis are asking for the public’s help identifying people involved in a street takeover that blocked officers from responding to a scene that left one woman injured.

A new map making its rounds online suggests Missouri may have far more fallout shelter locations than many realize, a Cold War legacy that has people wondering how many of them are still functional today.

His family now faces an uncertain future after his arrest during the Trump administration’s immigration crackdown, but his wife tells FOX 2 News that at least they’ll face it together.

A vacant building in north St. Louis collapsed onto an adjacent home Sunday evening, trapping two children inside. A 16-year-old boy managed to pull his 4-year-old nephew to safety before firefighters arrived at the scene.

The Missouri Senate is considering a bill that would make insurance companies cover treatments for certain pediatric autoimmune disorders.

A former Missouri nonprofit executive was sentenced Monday for stealing nearly $20 million from a program meant to provide meals for low-income children.

Emergency management officials in Lincoln County say a coding error may have caused several tornado warning sirens to fail during storms that moved through the area Sunday.

St. Louis police responded to multiple shootings and street takeovers across the city from Saturday evening into early Sunday morning, leaving several people injured.

A man is awaiting extradition back to Belleville after being charged for one of two homicides in the city on Sunday.

An EF-0 tornado with peak winds of 85 miles per hour briefly touched down in rural southwest Illinois late Sunday afternoon.