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Two relatives are jailed for shooting at a vehicle, causing the driver to crash into a Berkeley home.

An officer with the St. Louis Metropolitan Police Department is in "critical condition" following a training exercise Wednesday morning.

A Bethalto, Illinois, woman who permitted her boyfriend to sexually abuse a child in her case was sentenced Tuesday to decades in state prison.

A motorcyclist died after a crash Tuesday evening in St. Charles County, according to the Missouri State Highway Patrol.

Missouri lawmakers are considering a bill that would require stricter proof of U.S. citizenship to receive food stamps and healthcare benefits in the state.

Cheers erupted Wednesday at Kennedy Space Center in Florida after NASA's long-awaited Artemis II launched into the sky, embarking on its historic mission to the moon.

The 114th Greater St. Louis Honor Flight departed from St. Louis Lambert International Airport for Washington, carrying a group of veterans from World War II, the Korean War and the Vietnam War for a day of recognition at the nation's capital, including a celebration of World War II veteran Bob Schultz's 104th birthday.

The Missouri attorney general is taking aim at the controversial drug, 7-OH and it's Kansas City-based maker.

Yahya Maly, 29, faces 21 felony counts involving seven alleged victims, and jury selection for his trial is set to begin Thursday morning in St. Louis County.

ST. LOUIS - A woman was killed in a shooting Tuesday night in north St. Louis. According to the St. Louis Metropolitan Police Department (SLMPD), the shooting occurred shortly after 9 p.m. in the 5100 block of Cote Brilliante in the city's Kingsway West neighborhood. The victim, a 55-year-old woman, was critically injured and was [...]

ST. LOUIS - A tale of two halves of the St. Louis region is in the forecast Wednesday, but everyone sees some rain and storms. Closer to a stalled out frontal boundary and farther north, along and north of I-44 in MO and I-70 in IL, rain and storms will be more numerous, especially early [...]

A new effort called "slam the scam" comes to St. Louis. It targets criminals who steal federal benefits from the elderly, the disabled, and U.S. veterans.

Ramón Urías launched his first home run with St. Louis and Andre Pallante combined with four relievers on a three-hitter as the Cardinals defeated the New York Mets 3-0 on Tuesday night.

Missouri Attorney General Catherine Hanaway announced a lawsuit Tuesday seeking to halt the sale of kratom products and one its byproducts known as 7-hydroxymitragynine, or “7-OH,” saying that the substances post serious health risks, and can even kill.

A juvenile is in custody following a shooting at McCluer South-Berkeley High School, according to the Ferguson Police Department.

Volunteers spent their Tuesday picking up and removing boat loads of trash at the Lake of the Ozarks.

St. Louis City SC announced a "Summer of Soccer" initiative Tuesday, featuring 40 days of soccer activities and youth programming. The program begins June 11 and concludes with the World Cup final on July 19.

Just ahead of Autism Awareness Month, a skating rink in St. Charles is introducing a new mission centered on inclusion.

A second-alarm fire destroyed a Maplewood home Tuesday, leading to a rescue effort that saved four dogs trapped inside the burning structure.

Law enforcement in Berkeley has confirmed they are digging up a yard after receiving a tip in a missing person case.