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Two St. Louis County men are charged in an armed carjacking and police pursuit earlier this month.

A Missouri family is holding onto hope after their 7-month-old was taken off the transplant list and his parents fight for their son's survival.

Opening Day for the St. Louis Cardinals is a tradition like none other. Tens of thousands will celebrate festivities in Downtown St. Louis and attend the first game of the new St. Louis Cardinals season.

A St. Louis County man will appear in court Thursday afternoon to face charges of sexually assaulting a rideshare passenger inside her home.

FBI officials are conducting an investigation at a building in Clayton, St. Louis County, under court-authorized activity.

Following the big warm-up, another strong cold front will usher in much colder air late tonight into Friday, with freezing/frost conditions possible Friday night into Saturday morning.

ST. LOUIS COUNTY, Mo. - Fire crews responded to a house fire early Thursday morning in Florissant. The fire occurred around 4:30 a.m. in the 700 block of Wilshire Drive. Officials said three people were inside the home at the time of the fire, and all were able to exit safely. An investigation into the [...]

Yahya Maly, 29, is facing 21 felony counts involving seven alleged victims and is scheduled to appear in court Thursday for a pretrial hearing.

UPDATE: The missing person has been located and is safe, according to the Florissant Police Department. ST. LOUIS COUNTY, Mo. - An endangered person advisory was issued Wednesday night after a man was reported missing in St. Louis County.

ST. LOUIS - We have another day of potentially record setting high temperatures on Thursday. Temperatures will top out around 90 F. The warmest first pitch temperature for the Cardinals season is 85 F in 2001. The record high for March 26 is 87 F set in 1991. We will likely beat both of those [...]

The St. Louis Cardinals open their 2026 season at home Thursday at Busch Stadium III against the Tampa Bay Rays. And, while many expect the stadium to be full or at near-capacity for the home opener, the rest of the season could tell a very different story in terms of home attendance.

A Boonville casino was robbed at gunpoint on Wednesday afternoon the Missouri State Highway Patrol (MSHP) says.

For families walking into St. Louis Children’s Hospital, the experience can be intimidating. But John Wishom has been changing that for more than 30 years with his humor, warmth, and positivity.

Major League Baseball is set to produce and distribute every Cardinals regional broadcast during the 2026 season through MLB.TV, locally branded as Cardinals.TV.

The Northeast Ambulance and Fire Protection District hosted a car wash fundraiser on Saturday to help raise money for a Safe Haven Baby Box.

From lifelong supporters to first-time attendees, fans of Saint Louis University basketball said they came together this season to celebrate a team that reignited pride and community spirit across campus and the city.

The City of Edwardsville, Illinois is moving forward with plans to build a $4 million downtown pedestrian plaza known as the Goshen Commons.

WASHINGTON (AP) — Robert S. Mueller III, the FBI director who transformed the nation's premier law enforcement agency into a terrorism-fighting force after the Sept. 11, 2001, attacks and who later became special counsel in charge of investigating ties between Russia and Donald Trump's presidential campaign, has died. He was 81. “With deep sadness, we [...]

Two people were killed and another person was injured in a shooting Saturday afternoon in north St. Louis, police say.

The St. Louis Board of Aldermen has approved a limited exception to the city's smoking ban in an effort to host an international cigar convention.