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A teen is being treated for smoke inhalation after he escaped from a house fire in Spanish Lake that happened Thursday morning.

Major League Soccer owners voted Thursday to shift the league's season to a late-summer to spring calendar in 2027, bringing it more in line with its international counterparts.

A St. Louis teenager fatally shot his neighbor after accusing him of stealing $20 from his wallet earlier this month, police say.

More than 1,000 unionized Starbucks workers went on strike at 65 U.S. stores Thursday to protest a lack of progress in labor negotiations with the company. The strike was intended to disrupt Starbucks' Red Cup Day, which is typically one of the company's busiest days of the year. Since 2018, Starbucks has given out free, [...]

Toll costs for Illinois truck drivers could increase 30% by 2027 under a new transit funding bill approved by state lawmakers last month.

ST. LOUIS – It’s a prominent architectural and event landmark in downtown St. Louis. The Dome at America’s Center which has gone by several other names in the past now celebrates 30 years of existence. Established on Nov. 12, 1995, the facility was first known as the Trans World Dome, named after Trans World Airlines [...]

FOX4 looks into how you can get help for a gambling problem ahead of Missouri's sports betting rollout.

A cherished holiday tradition returns to St. Louis. Thursday, Nov. 20 is Old Newsboys Day.

A St. Louis man was clocked at 117 mph during a police pursuit on Interstate 44 earlier this week, ending with his arrest, along with authorities seizing methamphetamine and a handgun.

The Illinois Department of Public Health (IDPH) is urging parents and guardians to discontinue use of a recalled brand of powdered infant formula which has been linked to 15 suspected or confirmed cases of infant botulism in 12 states, including Illinois, a news release says. The FDA has expanded its recall to all ByHeart Whole Nutrition [...]

The Festus City Council unanimously approved the annexation of several land parcels near U.S. Route 67 on Wednesday in anticipation of a potential data center development.

REYNOLDS COUNTY, Mo. - The Reynold's County Sheriff's Office announced Thursday morning that a suspect has been taken into custody in connection to a potential homicide. According to officials, Reynold's County requested the help of the Missouri State Highway Patrol around 11:15 p.m. Tuesday for a report of a potential homicide inside a home along [...]

A 65-year-old St. Louis woman was seriously injured in a crash in Macon County after her Toyota Sienna was struck by a Ford Explorer after she hit a deer.

Every week, FOX 2 is recording more than 10 shows to bring new content that you won't get anywhere else.

Millions of customers, current and former, were impacted by a pair of data breaches.

ST. LOUIS COUNTY, Mo. - A man was charged after firing a gunshot during a road rage incident in north St. Louis County. According to the North County Cooperative Police Department, the incident occurred around 3:15 p.m. Nov. 7. after the drivers in two separate vehicles both claimed to have been cut off at stop [...]

On Thursday, the Gateway Arch Park Foundation announced that demolition has started on the long vacant Millennium Hotel Site.

As Missouri's firearms deer hunting season begins this weekend, hunters in St. Louis and St. Charles counties are now required to test any deer harvested for Chronic Wasting Disease.

First responders are on the scene after a vehicle overturned at the intersection of 10th Street and Washington Avenue in downtown St. Louis.

St. Louis city officials are urgently searching for large sites to house families displaced by the May 16 tornado, with plans to open mass shelters by Dec. 1 to accommodate hundreds of families.