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Two people were hospitalized after their vehicle clipped the back of a tractor-trailer on Interstate 70 near the Stan Musial Veterans Memorial Bridge.

Homicide detectives with the Belleville Police Department are investigating after two men were found dead Sunday.

The Missouri Tigers were selected as a 10 seed in the upcoming NCAA Tournament on Sunday, meaning they'll begin their March Madness run against the University of Miami Hurricanes.

Sunday’s weather events will drastically drop temperatures overnight through Tuesday, and increase the probability of high winds and snow this evening.

The National Weather Service issued a tornado watch for all of the FOX 2 News viewing area. Separate tornado warnings are being issued for select areas in the bi-state area.

UPDATE: The precautionary boil order has been lifted as of Monday morning. According to officials, the water test concluded the water was not contaminated and is safe to consume. ST. LOUIS CITY - The City Water Division issued a precautionary boil water advisory for parts of St. Louis on March 15 after a 20-inch water [...]

ST. LOUIS - A significant crash on Interstate 70 West near Carrie Avenue caused major traffic disruptions overnight, prompting a swift response from police, firefighters and EMS. The incident led to the complete closure of all lanes, diverting traffic and creating substantial backups until the scene was cleared early Sunday morning. Authorities are now investigating [...]

A Wind Advisory is in effect from 10 a.m. today through 12 p.m. on Monday for wind gusts to 45+ mph. Strong southerly winds continue to ramp up through the morning. Temperatures will quickly warm to the upper 60s to near 70 ahead of our powerful cold front. A strong and fast-moving cold front barrels [...]

Our Lady of Lourdes in U-City is celebrating a classmate, Peter, that has now beaten cancer twice and is still undergoing treatment.

An Arnold family of 10 is finally back in their home one year after an EF-2 tornado forced them out of it and caused significant damage across their hometown.

“Saturation Saturday" is a coordinated enforcement effort focused on identifying impaired drivers during the St. Patrick’s Day holiday weekend.

Sunday will bring an action-packed weather day to the St. Louis region with severe thunderstorms, gusty winds, fast-dropping temperatures and perhaps even some snow all possible into Monday.

Democrats are fighting over a rare Senate opening in Illinois, with Tuesday’s party primary likely to decide the deep-blue state’s next senator. 

Music, food, fashion, and plenty of local pride marked 314 Day celebrations across the St. Louis region.

An altercation between two people led to a shooting Saturday afternoon in Overland, police say.

A Missouri man died Friday after scuba diving in the Florida Keys, authorities say.

The 2016 murder of Jocelyn Peters, a pregnant St. Louis teacher killed in a murder-for-hire plot, will be featured in Saturday's episode of true-crime series "48 Hours."

The St. Louis Billikens come up just short to the Dayton Flyers, 70-69, in a back-and-forth affair with a wild finish in the final minute in the Atlantic 10 Conference Tournament semifinals.

Police have identified a homicide suspect who was found dead at a south St. Louis hotel earlier this month. Investigators say the suspect died by suicide and was wanted in connection with the death of a missing woman.

One woman and one child are hospitalized with serious injuries after a dog attack overnight in Granite City, police say.