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A fatal shooting was reported at the 4100 block of Farlin Ave. in St. Louis, leaving one woman dead.

While some plants can be as small as an upset tummy if ingested by your dog or cat, others bring serious health issues.

One case of measles has been reported in Southern Illinois.

On Wednesday, the Army Corps of Engineers held an open house at the Florissant Municipal Court to discuss the cleanup efforts of nuclear waste.

A former employee admitted in court to smuggling drugs as well as knives into the prison.

More victims are coming forward in what police say is a home renovation theft case costing St. Peters residents hundreds of thousands of dollars.

Operation Food Search's St. Louis MetroMarket program launched this week, bringing fresh, affordable food to underserved areas in the St. Louis region.

Since Easter, St. Louis has experienced at least five homicides, but police say that overall murders are at an all-time low compared to last year.

A bipartisan group of lawmakers joined business leaders to express optimism over Missouri’s increasing role in the technology sector.

This time, the story takes place within the St. Louis Zoo, and animals like the sea lion are the understudies.

A Missouri woman is accused of stealing $174,000 in disability payments over 14 years, according to a new federal indictment.

For those craving the crispy deliciousness of fried chicken, food writers recently crowned one Missouri restaurant as the best in the state.

This summer, teens aged 13-17 will have the opportunity to participate in the Illinois State Police (ISP) camps.

As St. Louis native Jon Hamm stars in Apple TV+'s new hit series "Your Friends & Neighbors," the Emmy-winning actor has opened up about personal struggles that helped reshape his life, including a pivotal turn through rehab and a journey toward redemption.

Over the weekend, three separate sinkholes emerged through the City of St. Louis, damaging homes, swallowing streets, and even causing a bump, or rather a hole, in the road for the Go! St. Louis marathon this weekend.

Cape Girardeau emergency crews recovered the body of a missing Illinois man Thursday morning in the Mississippi River.

A new two-part series from "CBS Evening News" has brought renewed attention to decades-long concerns of nuclear waste contamination at Coldwater Creek and its devastating impact on St. Louis-area families.

After two decades of deadlines pushed back, the Department of Homeland Security is implementing its Real ID requirement in exactly two weeks. And more than half of Missourians are without one.

A Jefferson County man appeared in federal court Tuesday and admitted building and possessing a pipe bomb in the summer of 2023.

Shake Shack, a popular fast-casual burger chain, is preparing to open another St. Louis-area location. This time at the site of a former Fuddruckers in St. Louis County.