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A family is pleading for help finding 41-year-old Perrin Cooper, who has been missing from East St. Louis since Monday.

A Webster Groves family, led by three young kids, spent their Saturday running a bake sale and raising money for a good cause: To help animals in need.

For years, many people have said Carlinville, Illinois feels like it's right out of a Hallmark movie. Now, the small town could actually become the setting for one.

Hundreds of motorists gathered Saturday to take part in the "Angels of Abbey Gate Memorial Ride," an event held in memory of fallen U.S. Marine and Missouri native Jared Schmitz.

Missouri voters will decide on three statewide constitutional amendments in the November 2026 general election, headlined by Amendment 3, which could reinstate abortion bans across the state in most cases.

Joshua Báez became the first player to hit three home runs in his first three at-bats in the major leagues, leading the St. Louis Cardinals to an 8-4 victory over the Chicago Cubs on Saturday.

A fourth suspect has now been arrested and charged in connection with the murder of a mother who was fatally shot in front of her children earlier this year at a Ferguson gas station.

St. Louis police officers rescued a 6-month-old baby who was left unattended in hot car Saturday in north St. Louis. Both of the baby's parents were arrested shortly thereafter, police say.

A Major League Baseball debut for the history books: St. Louis Cardinals outfielder Joshua Baez hit a home run in each of his first three MLB at-bats. He's now the only player in baseball history to ever do that.

A teenager from mid-Missouri died when he drowned in a swimming pool Friday evening, according to the Missouri State Highway Patrol.

E.coli levels in the Big River near Leadwood, Missouri, are slightly improving, but remain high, one week after state officials identified raw sewage in the river and problems with the city's wastewater treatment system.

ST. LOUIS - Scattered rain across mainly our far northern counties will gradually move out of the area this morning. We’ll then see decreasing cloud cover, with temperatures heating back up into the mid to upper 90s, especially along and south of the I-70 corridor. The Extreme Heat Warning continues in this area through Sunday, [...]

A man was taken into custody Thursday after allegedly robbing a Chase Bank in Fairview Heights.

On Saturday, Aug. 15, the Elchert family will host its 3rd bake sale at their home down the road from in Webster Groves from 10 a.m. to noon. If you plan to attend, there will be signs in the area to guide you.

Travis Askew lives in East St. Louis and takes westbound I-64 to work. He’s bracing for a closure that was scheduled to begin at 9 p.m. on Friday and last until 5 a.m. on Monday, August 24.

It’s St. Stephen Catholic Church on South Main, where someone reportedly stole copper downspouts – right next to Caseyville, P.D.

Homicide detectives are asking for the public’s help identifying the person or people responsible for the deadly shooting of a man in the city’s Baden neighborhood.

At long last, the St. Louis Cardinals are promoting Joshua Baez, minor league baseball's home run leader this season, for his major league debut.

Multiple suspects were taken into custody after a car wanted in connection with a burglary struck a St. Louis Metropolitan Police Department vehicle while officers attempted to make a traffic stop.

The Missouri Department of Transportation (MODOT) celebrated the 70th birthday of the launch of the construction of Interstate 70 that began in St.  Charles in 1956.