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A pickup truck driver fell asleep and lost control of their vehicle before plowing into a clinic for children with disabilities.

It's impossible to tell the story of soccer in the United States without mentioning St. Louis.

Two people were killed Sunday afternoon when a tornado touched down in rural Jefferson County, Illinois, as part of a day of active weather across the region.

The Madison County Sheriff’s Office is investigating after a woman was found dead late Sunday morning in Cottage Hills.

One man is dead and six people—including three children—suffered various injuries following a collision in north St. Louis County.

JJ Wetherholt hit two home runs and had three RBIs as the St. Louis Cardinals avoided a series sweep with a 12-10 win over the Kansas City Royals. Masyn Winn hit a three-run homer in the Cardinals’ five-run first inning and Iván Herrera hit a three-run home run in the fifth for a 12-7 lead. Lars Nootbaar and Alec Burleson hit RBI singles as St. Louis had a season-high 16 hits. Jac Caglianone hit a pair of homers for the Royals. St. Louis used seven relievers with Gordon Graceffo (5-1) pitching one inning for the win. Stephen Kolek (4-2) gave up nine runs in 1 1/3 innings.

With a tornado watch in effect across all Illinois counties in the FOX 2 News viewing area and westward into Indiana, we have at least two confirmed tornadoes.

One person is dead and two others injured in a single-vehicle crash along the riverfront in downtown St. Louis.

Thunderstorms with heavy rain are pressing across the region, with the potential severe weather developing this afternoon and evening.

Father's Day will be unsettled with waves of rain and storms moving across the area from late morning through the evening hours. Storms will be capable of heavy rain with amounts in the 1" to 3" range with some isolated pockets of 3+ expected. This could lead to localized flash flooding. This afternoon, as our [...]

One man was shot during a group altercation Saturday evening in north St. Louis County, police say.

BJ's Bar and Grill, a fixture in Old Town Florissant for seven decades, announced this week it will close its doors. The establishment, known for its pizza and authentic hometown atmosphere, has been a local favorite since 1955.

It's been a busy weekend for St. Louis City police. Officers are on the lookout for multiple "teen takeovers" that previously been planned across the city. Police are working to prevent them from happening and make sure things stay peaceful.

Father's Day will likely bring a mix of strong storms, heavy rain and flash flood threats to the St. Louis region.

Dustin May is a big reason why the future-focused St. Louis Cardinals find themselves in playoff contention in a season many didn't expect it. In the process, he's evolved from a logical trade chip to a potential building block.

One man has died Saturday afternoon after a crash in St. Louis' Downtown West neighborhood, police say.

Trump claimed there'd be “NO TOLLS” in the waterway during or after the ceasefire period unless the two sides fail to reach a final agreement by then.

The Ferguson Police Department is asking for the public's help in its search for a man who went missing Friday.

As spring gives way to summer, you may notice dead, leafless trees standing out in Missouri's green landscape. It's a growing trend among several tree species in the state, and experts say there are many reasons behind it.

SEATTLE (AP) — Christian Pulisic’s injury absence didn’t hurt the United States one bit. The Americans advanced to the knockout round of the World Cup without their injured star forward, beating Australia 2-0 on Friday for their second straight victory in the expanded 48-team tournament. The U.S. then won Group D when Paraguay beat Turkey [...]