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Four people were hospitalized, one of them a 12-year-old boy, following a six-vehicle crash on Interstate 270 in St. Louis County.

Two juveniles were arrested and their parent charged Friday after multiple fights at a fast-food restaurant in Fairview Heights.

No. 25 Missouri ended a nine-game skid against ranked opponents by blowing out No. 8 Florida 45-17. Austin Simmons threw for 340 yards and two touchdowns and Jamal Roberts ran for 211 yards and three scores. The Tigers gave coach Eli Drinkwitz his first regular-season win over a top-10 team in 11 tries with them. Missouri bounced back from a late collapse at Mississippi State last week and improved to 4-1 and 1-1 in the SEC. Florida was held to 325 yards of total offense, and Heisman Trophy candidate Jadan Baugh ran 12 times for only 13 yards.

A man and woman are in custody at St. Clair County Jail for a Washington Park murder over the summer.

A Calverton Park man is accused of raping his girlfriend, tracking her, controlling her income, and keeping her away from family and friends.

Homicide detectives with the St. Louis Metropolitan Police Department have identified a man killed overnight Friday morning in the city’s West End neighborhood.

A minibike rider was critically injured late Friday after a crashing in north St. Louis.

A St. Louis man remains jailed for stabbing a person and their dog at the Civic Center MetroLink last week.

One rural Missouri high school student has put himself in rarefied air.

St. Louis food creator Sarah Bites has visited more than 150 local restaurants and built a growing audience by helping people find their next great meal.

ST. LOUIS - We have a gorgeous weekend ahead! Expect plenty of sunshine on Saturday, with a slight increase in high clouds later in the afternoon and into the evening. Temperatures will climb into the low to mid 70s. Another chilly night is ahead, with lows ranging from the mid 40s to lower 50s. Despite [...]

Mason McTavish scored early and Joel Hofer recorded a shutout to lead the St. Louis Blues to a 4-0 victory over the Dallas Stars in their season opener.

The City of St. Louis has completed a $2.4 million renovation of the athletic field at Sumner High School in north St. Louis. The facility, named Tuskegee Airmen Field, honors seven Sumner graduates who served as Tuskegee Airmen.

A Belleville family is seeking answers after their loved one was hospitalized and remains in critical condition following an incident involving police and ambulance personnel.

The Missouri State Capitol dome glowed pink Thursday night in recognition of Breast Cancer Awareness Month, highlighting the importance of early detection, treatment, and support for those affected by the disease.

Both Kansas and Missouri are getting their time in the spotlight after being featured in the television shows 'COPS' and 'JAIL.'

Kansas City Chiefs starting right guard Trey Smith and running back Kenneth Walker have developed a unique bond in an unexpected way.

The former Indiana offensive lineman came to Chiefs minicamp as a tryout player, one of dozens of young prospects hoping to turn a few days of work into an opportunity.

Roosevelt High School launched a new event during this week’s homecoming activities, a sports showdown featuring students competing against local first responders.

What started as a project to restore an old stone church has grown into a much larger effort to bring new life to the small town of Bay, Missouri.