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One man is dead and three people have life-threatening injuries following a collision Sunday morning in north St. Louis County.

Defending champion Jesse Love won the Nu Way 225 at Worldwide Technology Raceway in Madison, Ill., securing his first victory of the season.

Alec Burleson hit a bases-clearing double, sparking the St. Louis Cardinals to a 3-1 victory over the Chicago White Sox to wrap up a three-game series.

Three people were arrested Saturday for participating in street takeovers in south St. Louis and downtown.

Steve McBee Sr., a Missouri-based farmer known for his role in a popular reality TV series, has been released from prison after serving two years for a multi-million-dollar federal crop insurance scheme.

An 80-year-old man wandered away from a nursing home early Sunday morning, prompting St. Louis Police to issue an Endangered SILVER Advisory.

Incumbent Mayor Brandon Johnson joins a crowded field of Chicago mayoral candidates for the Feb. 23, 2027, election.

El Grito Chicago is already underway in Grant Park, bringing together music, food, art and dancing to celebrate Mexican culture and pride. Also Sunday is the 26th Street Mexican Independence Day Parade, which kicks off in Little Village at 2 p.m. Additionally, there's a parade Sunday on the Far South Side, which starts at 1 p.m. near East 87th Street and South Commercial Avenue.

Homicide detectives with the St. Louis Metropolitan Police Department are investigating after a woman was found shot to death in the city’s Penrose neighborhood.

ST. LOUIS - We'll have a mix of clouds and sun Sunday with high temperatures in the upper 80s. It’ll be mostly cloudy overnight, with lows in the 60s. We could see a few spot showers Monday morning, mainly in our western counties, but rain chances will remain low overall. Clouds will decrease through the [...]

Randal Grichuk hit a two-run, two-out homer in the ninth inning as the Chicago White Sox snapped a four-game losing streak with a 6-5 win over the St. Louis Cardinals on Saturday night.

Rafael Navarro scored two goals for the second consecutive game to help St. Louis City beat Minnesota United 4-2on Saturday night and extend its unbeaten streak to 15 games.

The local chapter of the Tuskegee Airmen hosted free "discovery flights" on Saturday at the Spirit of St. Louis Airport. Kids had the chance to learned about the Tuskegee Airmen, aviation careers and STEM opportunities.

At long last, it was time to break out the red jackets for Albert Pujols and Yadier Molina.

One man is hospitalized with "serious injuries" after a stabbing Saturday afternoon in north St. Louis County, police say.

Five Missouri voters have filed a lawsuit against Secretary of State Denny Hoskins, seeking an estimated $80 million in damages for voters over his handling of a referendum challenging the state's 2025 congressional redistricting map.

Firefighters rescued a man Friday evening after he fell into a storm sewer nearly 25 feet underground in High Ridge, Missouri.

An experiment made with a 3D printer became an unforgettable gift for a St. Louis family. Now it’s become a full circle moment for a business owner and 3-year-old Lyla Whitley, and it all started on social media.

Nearly 20 years ago, St. Louis Cardinals fan-favorite David Eckstein was handed the keys to a bright-yellow Chevrolet Corvette at Busch Stadium. Turns out, that car wasn't his to keep.

An apparent explosion damaged multiple houses Saturday afternoon in Meadowbrook, Illinois, multiple witnesses tell FOX 2.