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Three people are dead after a multi-car crash Friday evening in Bellefontaine Neighbors, according to the Missouri State Highway Patrol.

Application rates at Missouri University of Science and Technology have declined, a shift university officials say is tied in part to shifts in international student enrollment, and the rise of artificial intelligence.

The St. Louis Cardinals host the defending World Series champion Los Angeles Dodgers this weekend at Busch Stadium. FOX 2 will carry the game broadcast for Saturday's contest.

ST. LOUIS - We'll have a mix of clouds and sun today with temperatures staying cool, highs reaching about 60 degrees. We could have a few spotty sprinkles across our southeast MO and southwest IL counties through the morning hours and potentially into the early afternoon. Sunday will be warmer with temperatures in the low [...]

WEST PALM BEACH, Fla. (AP) — Spirit Airlines, an impish upstart that shook the industry with its irreverent ads and deep discount fares, announced Saturday that it has gone out of business after 34 years. The ultralow cost airline that once operated hundreds of daily flights on its bright yellow planes and employed about 17,000 [...]

May Day' protests were held across the globe Friday. There were several notable, large protests across the U.S., including one right here in St. Louis. 

Jordan Walker was 4-for-4 with two doubles and two RBIs and the St. Louis Cardinals beat the two-time defending World Series champion Los Angeles Dodgers 7-3 on Friday night.

St. Louis Lambert International passengers can now use a tool to track shuttles from the airport’s parking partner, Super Park.  

A new coffee shop has launched in downtown St. Louis, revamping a former frozen yogurt business along Washington Avenue.

In honor of 100 years of “The Mother Road,” the Missouri History Museum is hosting the Route 66 Centennial Festival through Sunday.

Two of the most iconic ballplayers in team team history are headed into the St. Louis Cardinals Hall of Fame.

A newly released police report, involving a bar fight exposed in the past by FOX 2, shows local law enforcement found probable cause of crimes. A prosecutor in another county, however, declined criminal charges.

According to the St. Louis Metropolitan Police Department, officers responded shortly after 5:15 p.m. in the 5200 block of Vandeventer Ave. Police say both victims were women, and that they are ok following the shooting.

Six Flags St. Louis is reintroducing a chaperone policy for the park this season after a large fight involving teenagers occurred last Saturday outside the park gates. The new policy requires all guests 16 and younger to be accompanied by an adult 21 or older.

A $7.4 billion settlement involving Purdue Pharma and its owners took effect Friday. Both Missouri and Illinois are set to receive a share of settlement funds.

At St. Louis County Government Memorial Park, remembrance is more than a single moment. It is an enduring promise renewed year after year, name by name.

A St. Louis summer tradition is back tonight as "Sauce Food Truck Fridays" kicks off its 2026 season at Tower Grove Park.

Rising star Dylan Holloway has agreed to a five-year, $38.75 million contract extension with the St. Louis Blues.

Three dozen school districts across the state of Illinois are under formal investigation by the U.S. Justice Department.

Illinois Gov. J.B. Pritzker is recovering from a medical procedure he had on Friday and will put a pause on public events next week.