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Police are searching for two suspects accused in a deadly shooting at a south St. Louis gas station on Christmas Day.

Holly, a retired teacher from Johnston City, Illinois, accidentally won a $250,000 jackpot on the Illinois Lottery's $20 Magnificent Multiplier FastPlay game after intending to buy a $2 Booming Bucks ticket.

Three men are accused of sexually assaulting a woman over the weekend while their roommate, the victim’s boyfriend, was away from their Wright City home.

Is it cheaper to live in the City of St. Louis or its suburbs? The answer, according to a new study, may surprise you.

Starting next year, many Missouri schools will be required to roll out "Stop the Bleed" kits, following new statewide protocols aimed to help staff respond quickly to severe injuries and medical emergencies.

A Wentzville, Missouri, man is accused of a committing a violent break-in over the weekend.

The recall includes two different products, both made by the same Iowa-based company.

American Airlines is adding two new daily flights from St. Louis to Chicago, starting in February 2026.

Auditor Fitzpatrick is urging lawmakers to take immediate action to curb the trend of deficit spending before the state's General Revenue Fund is drained to "critically low levels."

ST. LOUIS - The gusty winds have continued to ease overnight, but it is still a breezy and cold start to Tuesday with wind chills in the single digits. Sunshine this morning will give way to increasing clouds this afternoon. It will be a bit warmer with highs pushing into the mid 30s. Waves of [...]

Several police agencies are responding to an incident in Foristell Tuesday morning.

In response to the temperature dropping below 20°F Monday, the Emergency Weather Response (EWR) hotline was activated in St. Charles, Warren and Lincoln counties.

According to facility officials, the truck was approaching nearby train tracks when it began reversing and collided with the facility’s gate and exterior fencing.

Temperatures in St. Louis plummeted dramatically from record highs on Monday, yet residents turned out in full force for Winterfest.

Over the last 24 hours, area fire departments have had to fight numerous weather challenges when arriving on scene. It's not uncommon for first responders.

It has been a jam-packed year of big weather stories in the St. Louis region.

It was another year of rewarding resolutions for the Contact 2 team.

City officials, the state and the St. Louis Board of Aldermen are battling in court over who has the authority to appoint an interim sheriff ahead of a March election.

A St. Louis County man is behind bars after he is accused of shooting his stepfather because of a dispute over the weekend.

A crash in north St. Louis quickly escalated to a shooting and ended with several suspects fleeing the scene.