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The historic Annie Malone headquarters in north St. Louis is facing renewed challenges as it has been broken into for a third time, compounding damage from a May 16 tornado and winter's burst pipes. Thieves are targeting the vacant building, stealing valuable materials and hindering ongoing restoration efforts.

More than a year after two young brothers were shot and killed in St. Louis, community members are offering a new reward in hopes of generating new leads.

An arrest warrant has been issued for a Warren County man accused of a plethora of fraud and theft charges in multiple Missouri counties.

Adolphus Busch IV, a member of the iconic Busch brewing brood who mostly kept himself at arm’s length from the family business, has died.

Two men from Florissant and Spanish Lake are accused of carjacking an auto parts employee at gunpoint and later robbing a pizza delivery driver the following day.

After spending more than three decades within the education system and state government, Missouri’s Commissioner of Education Dr. Kara Eslinger retired Monday.

A well-known St. Louis eatery woke up to a window shattered by an individual early Monday morning.

A Warren County woman faces felony charges after investigators say she exploited an elderly person out of tens of thousands of dollars while serving as the victim's power of attorney.

Three SWAT officers were injured during a standoff in south St. Louis Monday afternoon.

After taking home the title in 2025, Florissant’s Old Town Donuts was nominated again for the 2026’s America’s Best Donut Competition.

ST. LOUIS COUNTY, Mo. - A woman was charged after spraying bear mace at an adult and a teenager inside a store in Overland. According to the Overland Police Department, the incident occurred May 26 at a Dollar Tree in Overland. Police said Makiyah Steele (age not provided) sprayed an adult and a 15-year-old with [...]

LAKE OZARK, Mo. (AP) — A facility deep in rural Missouri promises relief for desperate parents whose adopted kids are struggling — a lakeside, summer camp-like academy where kids can heal by bonding with golden retrievers, and where caring employees “create joy.” The company that operates the place known as Calo Programs says it exists [...]

Lufthansa is temporarily increasing its non-stop international flights from St. Louis to Frankfurt to five days a week until October 20, in response to the consistent support of regional flyers.

The Alton Police Department is investigating a shooting that left one person dead and another injured Monday morning.

A St. Louis County man is accused of exposing himself inside a Maryland Heights restaurant.

The City of St. Louis will conduct an outdoor warning siren test Monday morning, marking a major step in ensuring all sirens are functioning following their failure on May 16, 2025.

ST. LOUIS - Police are investigating after a man was found dead Monday morning in north St. Louis. According to the St. Louis Metropolitan Police Department (SLMPD), the man was found a shortly before 8 a.m. on Kossuth and Vandeventer Avenues. An investigation into the incident is ongoing. This is a developing story; FOX 2 [...]

A tree caused a partial building collapse in St. Louis County, blocking Fowler Avenue and causing no injuries.

More than 4,200 customers in Missouri and 570 in Illinois are without power due to a severe thunderstorm in the St. Louis region.

Illinois lawmakers passed a nearly $56 billion state budget that includes new taxes, a pay raise for lawmakers, and a bill limiting students' access to cell phones during class, while a proposal to help keep the Chicago Bears in Illinois stalled.