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An investigation is underway after a crash involving a school bus Wednesday afternoon in Berkeley.

Six members of a St. Louis drug ring, including the leader, have pled guilty to various drugs and gun charges linked to two murders investigations.

The St. Louis Circuit Attorney's Office accepted a plea deal Wednesday in a 2019 fatal DWI crash.

A Maplewood police officer has been suspended with pay and is behind bars amid a child pornography investigation.

After a weekend of gun violence in downtown St. Louis, the Cardinals are working with several first responder agencies to ensure fan safety.

Police are asking for the public's help with finding a missing Minnesota woman who is possibly around the St. Louis area.

Where in the St. Louis area can you get some of the best french fries?

CODES, a new cannabis brand in Missouri, has launched with a 314-strain inspired by St. Louis. To mark the launch, CODES donated to St. Louis-based charity The Housing Partnership.  

ST. LOUIS -- Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine have launched a new podcast series called "This is Cancer." IT will feature patients and Washington University physicians having honest and raw conversations about being diagnosed. There are seven episodes in the first season, each covering a different type of [...]

One man targeted St. Louis-area Home Depot stores and Missouri’s unemployment insurance program in fraud schemes, pleading guilty to federal felony charges Tuesday.

Illinois Gov. J.B. Pritzker has signed a law providing full disability benefits to Chicago police officers and firefighters struck by COVID-19 before vaccines were available.

A federal appeals court has affirmed the conviction of the leader of an Illinois antigovernment militia for masterminding the 2017 bombing of a Minnesota mosque.

"Guardians of the Galaxy Vol. 3" just arrived to movie theaters last weekend, and it offers a nice surprise for fans from the St. Louis region, specifically St. Charles.

Thousands of American families are scammed into buying sick or dying puppies, according to a report from the Humane Society of the United States, with Missouri dog breeders generating the most complaints in the country.

The City of St. Charles and Ameren Missouri have reached an agreement granting the utility company access to city-owned property in order to monitor groundwater contamination at the Elm Point Wellfield.

KANSAS CITY, Mo. (AP) — Officials in Missouri's largest city are moving to declare it a sanctuary for people seeking or providing gender-affirming care, defying state officials who are intent on banning it for minors and restricting it for adults. A Kansas City Council committee approved such a resolution Wednesday. The full council will now [...]

Missouri Gov. Mike Parson has officially launched an online application for anyone interested in becoming the next St. Louis Circuit Attorney.

The St. Charles Parks and Recreation Department is closing the McNair Aquatic Facility, effective immediately.

O’FALLON, Mo -- Range USA, opened its 42nd location in O'Fallon, Missouri on May 8th, 2023. This is the 2nd Range USA store to open in the St. Louis market. At Range USA, customers can choose from a vast array of firearms, ammunition, and accessories, in addition to utilizing 20-25-yard shooting lanes and 25-person [...]

A doctor from Kansas has admitted to a role in a telemedicine fraud scheme for unnecessarily ordering genetic testing and orthotic braces, defrauding Medicare of about $16 million.