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A fatal crash was reported this early this morning a little bit before 4am on I-44 Eastbound past Antire Road, just before 141.

Fox 2 News received a copy of the inspection report completed from St. Louis County Public Health Thursday after inspectors visited Republic Services off I-55 and Bayless on March 15.

There was a long line of customers walking into the Bullpen Sports Grill in St. Francois County Thursday night.  The business owners held a fundraiser for the family of fallen Bonne Terre Police Officer Lane Burns.  

The family of a 27-year-old St. Louis woman is pleading for the public's help in finding her.

People across the state of Missouri are mourning the death of three police officers killed in the line of duty this month.

A man pleaded guilty Thursday to first-degree murder in the death of an Illinois deputy killed during a multi-state crime spree just days after Christmas.

Flags were lowered at half-staff to honor a Bonne Terre police officer killed in a motel shootout Thursday morning.

A new Lown Institute report shows hospital markets in large U.S. cities are racially segregated, and two Missouri cities are among the worst.

A nationwide lack of bus drivers that is also impacting the St. Louis region is to blame for the demise of the "Redbird Express" at least for 2022.

CHICAGO (WMBD) -- Six months after the disappearance and death of Illinois State University (ISU) graduate student Jelani Day, the FBI is still looking for new information that might explain what happened. The reward was initially posted in December 2021, and was part of a nationwide, coordinated, multi-platform social media campaign from the Jelani Day [...]

People with the Heartland virus disease, carried by the lone star tick, have been found in a dozen states, including Kansas and Missouri.

ST. LOUIS, Mo. - We’re excited to announce that we have newly redesigned our website here at FOX 2, which features a cleaner, more modern look and feel. We think you’ll love the new look at FOX2Now.com, which allows you to see more content and navigate stories easier than ever before.  The website is designed [...]

ST. LOUIS - St. Patrick's Day was Thursday and Dogtown was busy celebrating! The neighborhood hosted its first festival Thursday since 2019. The 2020 St. Patrick’s Day celebration was canceled just six days before due to the pandemic. Dogtown United said street closures and parking restrictions ahead of the annual festivities began at 6 a.m. [...]

The St. Louis County Prosecuting Attorney's Office charged a 37-year-old on Wednesday for allegedly having inappropriate sexual contact with two children under 12 years of age.

Authorities in southern Missouri are investigating a massive chain-reaction crash in Mississippi County that involves dozens of vehicles.

One man is in custody and facing charges of drug possession and stealing after allegedly driving off with a school bus in central Missouri.

Animal-to-human transmission of the Highly Pathogenic Avian Influenza is extremely rare.

Granite City Police were called to a mobile home fire on W. Chain of Rock Road around 11:40pm last night. It was reported that two people were trapped inside.

Bonne Terre Police responded to a disturbance call at a Motel 6 off Highway K a little before 12:30am this morning.

Parkway West Middle School wants to make sure its ahead of future bullying issues on TikTok.