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College football is back! The Missouri Tigers open a new season Thursday evening, a head start as most Power Five Football teams return to game action this weekend.

On August 31, 4 Hands Brewing’s new tasting room location will open at The District in Chesterfield.

One man died in a crash involving two motorcyclists Wednesday evening in Jefferson County, according to the Missouri State Highway Patrol.

A man wanted on warrants for St. Louis-based crimes and federal treason charges was arrested earlier this week in southern Missouri.

A two-day binational conference began on Wednesday with leaders from the United States and Mexico earmarking future projects to spur economic development on the border, and trying to solve a water crisis that is plaguing both countries.

Music lovers are coming from all across the region to attend this year's 'Music at The Intersection' Festival, but this year there's a connected event for anyone interested in the music industry.

ST. LOUIS -- A campaign to prevent drunk driving through ride-sharing apps is expanding to college campuses nationwide before football season. Anheuser-Busch, Mothers Against Drunk Driving, and Uber launched the Decide to Ride campaign in 2021. Nearly 12,000 people have used Uber ride-share discount codes to get home safely. “Football season is a time for [...]

Four biker friends are putting a plan to the pavement for an adventure of a lifetime that led to the last frontier, 'Alaska.'

Missouri Democrats are planning to open up next year's party-run presidential preference primary to 17-year-olds, but only if they turn 18 before the November 2024 election.

SSM Health St. Clare Hospital in Fenton and St. Louis Area Foodbank are hosting a drive through food fair Thursday.

A new partnership is launching in St. Louis County to fight the opioid epidemic.

Thursday is International Overdose Awareness Day, a day to remember those who died from drug overdoses and support the families and friends affected by their

For the fifth day in a row, a significant Illinois health care provider is experiencing a major technology system outage. The problem is impacting facilities operated by the 'Hospital Sisters Health System,' or HSHS.

Peoria police have confirmed that five to six people were shot in South Peoria late Wednesday night.

On Wednesday night, 46 members of Missouri Task Force 1 sat stationed in Panama City, Florida, as the storm Idalia made its way through the Sunshine State and up to the nation’s southeast coastline. Missouri’s Task Force 1 is now ready to respond to whatever may arise.

It's the second full moon of the month, hence the blue moon moniker. At 222,043 miles away from Earth, it's about 100 miles closer than any other supermoon this year.

As Missouri's judicial system hits a huge milestone with court records being available online, a top state lawmaker recommends people check to see if their private information has been posted.

Surveillance video obtained by FOX 2 shows a thief entering a Central West End parking garage and stealing a disabled man’s specialized tricycle.

St. Louis City SC fans flocked to the Downtown West neighborhood Wednesday night. They were cheering on a team that exceeded expectations in its inaugural season. The team appears to be playoff-bound with one of the best records in MLS.

A frightening rollover hit-and-run crash on Interstate 55 has been solved, according to police and prosecutors, with the help of the suspect’s own in-vehicle cameras. Court records reveal the trail of evidence begins with video of the suspect stumbling into his car before the crash.