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The St. Louis Blues part ways with two more veterans, trading captain Ryan O'Reilly and Noel Acciari to the Toronto Maple Leafs.

Mardi Gras weekend kicks off in St. Louis on Friday night with the Mayor's Ball. It's the second year the ball is held at Union Station.

A Missouri program is trying to help pediatricians combat a growing mental health crisis. 

PARK HILLS, Mo. — When you think of your typical Airbnb, it's likely that staying in a Native American style tipi doesn't come to mind. That's because there's nothing typical about staying in a Airbnb tipi. According to the owners (and more than 500 positive reviews left by those who've experienced this unique retreat in [...]

SPRINGFIELD, Ill. (WCIA) -- Governor J.B. Pritzker has signed a bill into law that removes barriers for transgender Illinoisans looking to change the gender on their birth certificate. Previously, the Vital Records Act required a statement from a licensed health care or mental health professional in order to create a new certificate with a different [...]

Hate stairs and love horses? This converted stable in rural LaSalle County may be your perfect home.

An El Paso man allegedly smuggled a shipment of narcotics to St. Louis, where he was arrested during a traffic stop earlier this month.

Two suspects were arrested and one remains wanted after breaking into a Ladue home Friday afternoon.

A former St. Louis police officer was acquitted Friday in a rape case filed after two former colleagues said they were assaulted more than a decade ago.

Missouri Attorney General Andrew Bailey has joined 25 other states in a lawsuit challenging new federal regulations on pistols with stabilizing braces.

FOX 2 reporter Blair Ledet features stories Honoring Black History in St. Louis during this special program.

Scott Rolen, one of the most decorated third basemen of his era, will enter the National Baseball Hall of Fame with a Cardinals cap on his plaque.

Police are investigating after a teacher found a loaded gun in a five-year-old's bag at a Town & Country school.

Two people are behind bars after a recent traffic stop in St. Louis County led authorities to a shipment of illegal drugs.

Ka-Kaw is once again the law as the St. Louis Battlehawks have returned for the XFL relaunch!

One teenage girl has died and five other teenagers are hurt after a crash overnight in St. Charles County.

A federal judge sentenced a man to prison Thursday after he obtained hundreds of counterfeit phone cases with the intent to resell them in southern Illinois.

If you're planning to venture out for St. Louis Mardi Gras festivities this weekend, make sure you plan ahead.

Dr. Anthony Fauci, the former chief medical adviser to the President of the United States, will give a speech to some graduating students at Washington University this spring.

ST. LOUIS -- Some say it is the social event of the year. Get your tuxes, your gowns, and don't forget your mask. The big Mardi Gras parade is this weekend in St. Louis and it kicks off with the Mayor's Ball Friday night.