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More than 40 dogs will be looking for new homes after being rescued from a woman living in Newton County, just outside of Joplin. 

An appalling, daytime, execution-style murder captured on video has people wondering what has become of St. Louis.

The family of Bryanna Dentman-Johnson is mourning the loss of the teen, whom they described as strong, independent, and prayerful.

A St. Louis resident called FOX 2's You Paid For It team after glass from the windows of an abandoned house fell to the ground, nearly hurting her grandchildren.

FOX 2 spoke with Charl “Priest” Howard, who’s now wearing an ankle bracelet as he still waits for trial years after his arrest.

A former Missouri state representative has been sentenced to six years and three months in federal prison without parole for fraud schemes involving medical clinics in southwest Missouri.

The two planets have been creeping closer together all month, and they will reach conjunction on the evening of Wednesday, March 1, when they will be closest on our sky's dome.

"Goldynado" is back in full force. The dynamic duo accomplished something Tuesday that they had yet to do in two seasons as St. Louis Cardinals teammates.

A former Chillicothe, Missouri, respiratory therapist named Jennifer Hall is charged with first-degree murder in a 2nd patient's death in 2002.

Freddy’s Frozen Custard & Steakburgers will open a location within the St. Louis Cardinals' home venue next month. Fans can find it at the ballpark’s Budweiser Terrace section in right field.

After moving three high-profile players in as many weeks, the St. Louis Blues might not be done making moves before Friday's NHL trade deadline. The biggest mystery of all... What's next?

JEFFERSON CITY, Mo. (AP) — Survivors of a deadly school shooting in St. Louis on Tuesday shared art, music and stories about gun violence at the Missouri Capitol while advocating for lawmakers to act. “We want to hear the specific actions you are taking to prevent tragedies like this one from happening again in our state and [...]

Nearly four dozen mixed-breed dogs and puppies have been taken from a hoarder in rural Missouri and are being brought to the Humane Society of Missouri's headquarters in St. Louis.

Here's a lovely-looking estate with a fairy tale feel, spread out across more than 15 acres, with a skyline and landscape so colorful you'd swear Thomas Kinkade painted it.

A suburban Chicago sheriff's deputy suffered serious injuries when the driver of a pickup truck opening a beer ran a stop sign and crashed into her squad car, a sheriff said Monday.

It is somewhat of an unusual phenomenon to have Northern Lights, or the aurora borealis, visible as far south as northern Missouri or central Illinois. However, it does happen from time to time when the solar winds are stronger and send electrons and protons streaming toward the earth's upper atmosphere. That collision produces the amazing [...]

Investigators have identified four people who died in a St. Louis hit-and-run crash over the weekend.

Popular grocery store chain Dierbergs is coming to University City. City council members approved a development plan Monday for Dierbergs.

One of the St. Louis region's biggest ambassadors in Hollywood is now engaged. Mad Men star Jon Hamm is now engaged to Anna Osceola.

A woman is accused of headbutting and kicking a deputy moments after her arrest in southern Illinois.