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St. Louis Ovarian Cancer Awareness is hosting its annual 5K Run and Walk, the largest event in St. Louis dedicated to supporting women battling ovarian cancer.

It's officially the end of an era. Albert Pujols and Yadier Molina have played their final MLB games.

Stadium packed a record-breaking crowd for Game 2 of the National League Wild Card Series, despite the Cardinals losing the best-of-three series in two games.

The Philadelphia Phillies stun the St. Louis Cardinals with a two-game Wild Card Series sweep, marking an end to the Cardinals' 2022 season.

One man and two women face criminal charges in a shooting investigation also tied to a home invasion and armed robbery in Belleville.

Two-time National League MVP Bryce Harper capitalized on a first-pitch curveball as the Philadelphia Phillies jump out to an early 1-0 lead over the St. Louis Cardinals in Game 2 of the Wild Card Series.

More than 100 people ran and walked Saturday at Bella Fontaine Park to raise awareness on domestic violence and abuse.

Resources like utility assistance, recruitment for city jobs and health checks were all set up Saturday for the "All Hands On Deck" community event. City leaders say they’re working to make a positive for underserved community members in St. Louis.

A mother whose son died less than an hour after he was transported from a Missouri jail to a state prison has won a $1.2 million settlement in a case that helped lead to suspensions, firings and reforms.

The Cardinals will use a similar lineup to Friday, but with one notable change. Juan Yepez, who broke a late scoreless tie with a two-run home run in Game 1, enters the starting lineup for Game 2.

The Sierra Club’s “Dirty Truth About Utility Climate Pledges” report gave Evergy an 18% for its investments in clean energy and moves to retire coal plants. Ameren Missouri got a 32%. 

Two teenagers are in police custody and one faces criminal charges after a spree of St. Louis County burglaries over the summer.

A federal judge has sentenced a St. Louis man to 19 years in prison over a pair of armed carjackings nearly two years ago.

A Family Dollar employee in south St. Louis is recovering after being shot while he tried to confront two "frequent shoplifters."

City police are investigating the shooting of a Lyft driver.

The win-or-go-home, one-game Wild Card rounds for the postseason are no more. A new format change in 2022 gives the St. Louis Cardinals new life after a scenario Friday that might have ended their season in previous years.

The Weldon Spring Site is located in St. Charles County, 30 miles west of St. Louis. It used to be the site of the 1956 Weldon Spring Chemical Plant.

NASA confirms that a St. Louis exorcism teen grew up to work at the government agency. 

With Halloween approaching, temperatures dropping, and football season entering its first full month - there are several activities you and your family could get involved in.

The Cardinals are hosting the Philadelphia Phillies in a best-of-three Wild Card series at Busch Stadium.