FOX 2 📺

A busy stretch of Interstate 64 flooded in St. Louis during rush hour Friday afternoon due to a water main break. Fire crews rescued one family after their minivan ended up stuck in water.

Kenley Jansen blew a ninth-inning lead for the second straight day when shortstop Kiké Hernández’s throwing error on a potential game-ending double play allowed Nolan Gorman to score the go-ahead run in a three-run ninth inning, lifting the St. Louis Cardinals to a 4-3 victory over the Boston Red Sox on Saturday.

If you're passing through the Midwest for a vacation and you're hungry, hopefully St. Louis is on your way. One well-known barbecue joint in the Gateway City takes the title as the "best road trip food" in Missouri.

Two teenagers are hurt after a pair of early-weekend drive-by shootings in St. Louis. The victims, two 16-year-old boys, were both treated for critical injuries.

Missouri State Highway Patrol is investigating a train incident that hit and killed a one-year-old child Saturday morning.

Severe weather is moving to the east, but it led to some significant hail Saturday afternoon in the St. Louis region, especially in St. Charles County.

St. Louis manager Oli Marmol announced before Saturday’s game against the Boston Red Sox that Willson Contreras will be back behind the plate on Monday night when the Cardinals open a homestand against the Milwaukee Brewers.

Defender Rafael Czichos scored late in the first half and Chris Brady made it stand up to lead the Chicago Fire to a 1-0 victory over St. Louis City on Saturday.

A Missouri man was sentenced to decades in prison after pleading guilty to child sex crimes in Illinois.

The latest Missouri legislative session ended Friday, and so did a GOP-backed attempt to change control within the St. Louis Police Department.

Companies, families and friends lace up their shoes to get some good exercise, all while promoting heart disease awareness.

Some severe thunderstorms, gusty winds and small hail chances are likely Saturday from the afternoon to early evening hours in the St. Louis region.

A gunman shot a driver and a passenger on Interstate 70 overnight in St. Louis. One woman shot suffered critical injuries.

Don Denkinger, a major league umpire for three decades whose blown call in the 1985 World Series overshadowed a career of excellence, died Friday. He was 86.

From the first coffee houses in the Ottoman Empire to Boston's London Coffee House, cafes have always been an egalitarian place to gather, sip, and share ideas, many of which have changed the world. During the Enlightenment, cafes would regularly entertain the likes of Voltaire, Rousseau, Benjamin Franklin, Thomas Jefferson, and Isaac Newton. Later, Simone [...]

This morning, cars are moving again in both directions on I-64 near Hampton after a massive water main break.

Thousands of people are expected to participate in the St. Louis Heart Walk this morning.

This morning, the weather started off mild and humid.

For decades, the organization has assisted refugees in making St. Louis their new home. Today's drive supports refugees from Afghanistan, Haiti, the Congo, Cuba, Syria, and others.

The St. Louis Dental Center is helping to make oral healthcare available to everyone in need regardless of economic, cultural, or linguistic backgrounds by training international dentists and breaking language barriers.