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Family and friends will gather Thursday in St. Louis to remember 14-year-old Tyre Sampson, who fell to his death from an amusement park ride last week in Orlando, Florida.

Detectives arrested a 47-year-old man in connection with a homicide that happened earlier this week in Overland.

Cale Douglas Clayton, of Drexel, Missouri, has been charged with numerous crimes connected to the January 6 riots at the Capitol.

ST. LOUIS, MO - The lockout is over and we are now just one week out from the start of the St. Louis Cardinals season. Opening Day at Busch Stadium will be April 7, 2022, against the Pittsburgh Pirates.

Police say one man is responsible for most of the illegal dumping on the streets of Kinloc

The National Weather Service has issued a freeze warning tonight for portions of southern Illinois and eastern Missouri.

The Republican-led Missouri House is set to pass legislation to defund Planned Parenthood and allow wrongful death lawsuits in rare cases when infants are born alive after an abortion attempt and the infant then dies or is injured.

ST. LOUIS--In a new interview, former St. Louis Cardinals manager Mike Shildt is shedding new light on the moment his eighteen years with the organization, including parts of four seasons as manager came to a surprising end last October when he was fired. Shildt spoke to USA TODAY's Bob Nightengale in a story published Thursday [...]

President Joe Biden on Thursday ordered the release of 1 million barrels of oil per day from the nation’s strategic petroleum reserve for six months in a bid to control energy prices that have spiked amid Russia's invasion of Ukraine.

A teenager is dead and a woman seriously injured in a collision on Highway 50 near Union, Missouri.

According to the Missouri State Highway Patrol, the crash happened just after 1 a.m. Thursday in the northbound lanes of the interstate, just north of Imperial Main Street.

Two St. Louis firefighters were injured after responding to a vacant house fire in south city before dawn.

Authorities in north St. Louis County are investigating a murder and searching for a shooter Thursday morning after Northwoods Police came under fire while responding to an emergency call.

A triple shooting near Saint Louis University leaves two dead and another person injured.

Police are responding to an incident in north St. Louis County Wednesday night.

The Missouri State Highway Patrol (MSHP) has a "wake-up call" for Missouri drivers, especially those in St. Louis County. MSHP reports a 15-year high in traffic fatalities in 2021. 

There were multiple water rescues in St. Clair County after rain showers caused some flooding Wednesday night, according to authorities.

There are plans for a new amusement park planned in Wentzville. Spirit of Discovery Park would only be the second fully-inclusive park in the world.

The St. Louis Metropolitan Police Department solved a decades-old mystery with the help of a new and unique DNA project.

Crowds packed the Enterprise Center to see Sir Elton John perform in St. Louis for the last time on his "Farewell Yellow Brick Road” tour.