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There’s still no definitive answer on what’s causing it, but we’ve discovered some new leads and closed the door on some other theories.

The director of the Centers for Disease Control and Prevention visited St. Louis on Thursday, and she said that the agency is prepared for another COVID variant or pandemic.

A man has died after being hit by three vehicles in downtown St. Louis Thursda

Ferguson native Calvin Harris, II is back home as the newly appointed Chief of Staff for St. Louis County Executive Dr. Sam Page. 

The Ballwin Police Department is mourning the loss of a beloved officer who died suddenly at his home.

St. Louis Alderman Joe Vaccaro claims that Police Chief John Hayden offered to fix tickets from a February 10. Traffic stop. Hayden says Vaccaro's actions in the stop should merit an apology to the officer.

ST. LOUIS - St. Louis area real estate's median listing price has gone up by $17,000 from January to February according to Realtor.com's monthly housing trends report. U.S. homes hit an all-time high median listing price of $392,000 in February, according to that report. It found that the St. Louis metro area's median listing price [...]

A statewide drill is scheduled for next week.

One of the last mask mandates in the state of Missouri will expire this weekend.

ST. LOUIS - St. Louis CITY SC signed a new forward for their inaugural season. Forward João Klauss, 25, was signed as a Designated Player pending his ITC, medical check and work authorization. He is currently on loan at Sint-Truidense V.V in Belgium. He will join St. Louis CITY SC via a transfer from German Bundesliga club [...]

Russian forces seized a strategic Ukrainian port and besieged another Thursday in a bid to cut the country off from the sea, as the two sides headed for another round of talks aimed at ending the fighting that has sent more than 1 million people fleeing over Ukraine's borders.

Collinsville police shot and killed a 45-year-old man who fired shots at officers Wednesday night, according to authorities.

CALLAWAY COUNTY, Mo. - An 8-year-old boy from the St. Louis area died in a crash late Wednesday night. The crash happened at about 9:40 p.m. when a Mazda 3 with a 23-year-old woman driver, a 40-year-old woman passenger, an 8-year-old boy passenger, and a 2-year-old boy passenger stopped in the right lane of westbound [...]

ST. LOUIS - A crash occurred early Thursday morning in south St. Louis. The multi-car crash happened at about 6:30 a.m. on 55 northbound near Arsenal. FOX 2's Bommarito Automotive Group SkyFOX helicopter flew over the scene. There was a large police presence at the scene. FOX 2 will continue to update this story with [...]

ST. LOUIS - CDC director Dr. Rochelle Walensky will visit St. Louis Thursday morning. She will be at the Washington University School of Medicine to discuss the pandemic. This is a virtual event geared toward faculty, students, and medical trainees, but it is also available to the public. The school said if you miss the live [...]

ST. LOUIS - The St. Louis area has clear skies Thursday morning. It will be mostly sunny and cooler Thursday with highs in the mid-50s. Warmer temperatures move into the area Friday with temperatures in the 60s. Expect wet weather this weekend. It will be dry Saturday morning, but expect showers and a chance of [...]

ST. LOUIS COUNTY, Mo. - A north St. Louis County neighborhood lost power early Thursday morning when a woman drove into a utility pole. The crash happened at about 12:45 a.m. on Chambers Road at Green Valley Drive. Medics treated the woman on the scene for her injuries. Crews will have to replace the pole [...]

ST. LOUIS - A Missouri State trooper was injured when a driver crashed into his patrol car early Thursday morning. The crash happened just after 12 a.m. when a woman plowed her car into the back of the trooper's vehicle along northbound I-270 near Tesson Ferry Road in south St. Louis County. The trooper had to be [...]

A 47-year-old man was killed in a crash on Interstate 255 in Collinsville Wednesday night.

There are one billion users on the app TikTok and it raked in 4.6 billion dollars in revenue in 2021. On Wednesday, Missouri and Illinois' attorney generals announced they are joining in on a bipartisan nationwide investigation into TikTok.