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The streets of Soulard were filled with dogs as they—and their humans—took part in the 29th annual Purina Pet Parade.

Stacker compiled a list of counties with the highest deaths from COVID-19 in Missouri using data from U.S. Department of Health & Human Services.

Firefighters are battled a blaze at a two-story, 10 unit apartment in Cahokia Heights, Illinois, Saturday afternoon.

ST. LOUIS - The St. Louis Metropolitan Police Department and the St. Louis Cardinals have partnered with the American Red Cross, to host a blood drive at Busch Stadium today to help with the shortage of blood supplies as hospitals and blood banks across the region face a critical need. This partnership is to help [...]

A St. Louis man is now alive thanks to an organ transplant team that persevered through incredible odds. That team had the task of transporting a pair of lungs. Little did they know, the weather would get in their way. 

The Missouri State Highway Patrol is investigating a fatal crash in the westbound lanes of Interstate 44 in Franklin County.

Consumers in Alabama, Arkansas, Louisiana, Mississippi, Missouri and Tennessee are advised not to use a variety of Family Dollar products, including foods, cosmetics, animal foods, medical devices and over-the-counter medications.

Bi-State Development is trying to give the failed Delmar Loop Trolley a new lease on life. Right now, the trolley is shut down.

ST. CHARLES, Mo. -- After the ice and snow stopped falling, it was time to clean up and clear out a path. It's a task some people dread, but a St. Charles restaurant owner took it upon himself to clear and salt the sidewalk for every business along North Main Street.

A judge ordered Tasha Haefs to undergo a mental exam after she was charged with murder in the death of her 6-year-old son in Kansas City.

An O'Fallon, Missouri man was arrested and charged with drunk driving after police said he crashed into a house with the homeowner inside.   

How would you like to pay less for groceries? It's something Missouri lawmakers are discussing, but paying less could mean it's costing public school districts across the state. 

Online food deliveries have exploded during the pandemic. But when you place your order, do you really know who’s cooking your food?

NEW YORK (AP) — One day after Major League Baseball owners and players met for just 15 minutes in a bid to find progress to end a lockout that threatens to jeopardize the start of the season, MLB announced Friday that spring training games through March 4 have been canceled. What was supposed to be [...]

(STACKER) -- The vaccine deployment in December 2020 signaled a turning point in the COVID-19 pandemic. By the end of May 2021, 40% of the U.S. population was fully vaccinated. But as vaccination rates lagged over the summer, new surges of COVID-19 came, including Delta in the summer of 2021, and now the Omicron variant, [...]

President Joe Biden said the door is still open for diplomacy, but he's "convinced" Russia will invade Ukraine. At a news briefing Friday, he reiterated no U.S. troops would fight in Ukraine, but America would provide support.

SPRINGFIELD, Mo. -- Vicky Hartzler, U.S. Representative for Missouri's 4th District and one of the candidates hoping to earn the Republican spot on the ticket for Roy Blunt's Senate seat, says she is excited about the support she's receiving in her campaign. She spoke to Ozarks First about what she would like to see accomplished [...]

If you're looking to adopt a puppy, we know of one that is ready to get out of the shelter.

Missouri Department of Conservation officials sent the birds for testing after the department's own physical exams of the birds found no signs of wounds.

ST. LOUIS - Friday morning after Thursday's winter storm created uncertain road conditions for commuters. The road conditions varied on Friday morning. Many highways and other main arteries in St. Louis County were in good shape, but the side streets and subdivisions were a much different story. FOX 2 crews encountered icy and slick conditions [...]