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The Anheuser-Busch family welcomed four baby Clydesdales; the colts will play a special part in a new Budweiser football tradition this Sunday.

A man in Columbia, Illinois, said his dreams of opening his restaurant are shot after the requirements put forth by the city were so unclear.

The Washington, Missouri, City Council, by a vote of 5-3 on Monday, rejected a request for a special use permit to operate a short-term rental on Riverview Place.

Residents in Foley, Missouri, lit up social media last week with posts about police investigators searching an area near where Bianca Piper disappeared in 2005.

After St. Louis police reported 149 cars stolen in a single week, a new wave has begun.

Check your tickets - here are Monday's Powerball numbers for the estimated $747 million jackpot.

St. Charles residents will head to the polls on Tuesday to decide the top two mayoral candidates who will move forward to a general election in April.

A desperate tenant contacts FOX 2’s You Paid For It team to get the East St. Louis Housing Authority to finally take care of a years-long problem at her apartment.

On a mild Monday afternoon, the shelves are stocked, and business is steady at Hippos Dispensary in Chesterfield.

A bipartisan group of Missouri lawmakers wants to extend Medicaid coverage for new moms and their babies.

As they welcome Super Bowl fans to their state, Arizona's indigenous communities are also calling for fans to respect their culture.

The western monarch butterfly has been struggling, but the population is showing signs of improvement. It's a sign conservation efforts are helping.

A manufacturing facility in Chicago Heights was destroyed in a massive fire Monday morning.

The Fairview Heights Police Department is still piecing together the events of Saturday night, when they were called around 10:30 for multiple fights at a Sky Zone trampoline park.

A community is in mourning after three Lincoln County High School students were killed in a crash early Sunday morning. Two others survived the wreck but are injured.

New guidance from the American Academy of Pediatrics says physicians should be more proactive when it comes to treating childhood obesity.

A South Roxana, Illinois, man could spend the rest of his life in prison after being accused of sexually assaulting children for the past several years.

With so many natural wonders in Missouri, there's never a lack of places to explore in the "Show Me State."

The president of the national NAACP is urging Missouri Gov. Mike Parson to halt the execution of Leonard Taylor, who is scheduled to die by injection Tuesday for the deaths of his girlfriend and her three children.

ST. LOUIS -- Steve’s Hot Dogs, The Fountain on Locust, and Alpha Brewing are among several high-profile local vendors working together on a new development at 5232 Delmar Boulevard. The event and dining space called will be called Maker's Locale and the complex is expected to open this fall. The idea is to create a [...]