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Investigators say a BNSF train derailed around 4:18 p.m.

According to the probable cause statement, the 57-year-old was a patient at the hospital, but he was released "against medical advice."

In a show of solidarity, Boeing workers on the west coast have raised donations for employees on strike in St. Louis.

BackStoppers, a St. Louis nonprofit that supports families of first responders killed or injured in the line of duty, is now assisting the family of a fallen Sikeston police officer.

Wentzville Crossing shopping center is set to welcome a new Burlington department store on Friday, Oct. 17.

A Florissant man faces several charges after hitting a person with his car in the parking lot of West County Mall.

Embattled St. Louis Sheriff Alfred Montgomery will remain in office for now, a judge ruled Friday, just one day after he was indicted on five new federal charges and ordered to house arrest.

Attorneys representing 17 Cardinal Ritter College Prep football players and their families say they are launching an independent investigation after players, coaches and staff from the St. Louis school were pepper sprayed by police after some fighting at a game in Ohio last week.

A woman who allegedly served as a getaway driver to help others steal several cars from a south St. Louis County repair shop last year now faces felony charges.

St. Charles County paramedics have started training on a new breakthrough medical device called Life Flow.

A 34-year-old man from Mexico died while in the custody of U.S. Immigration and Customs Enforcement (ICE), at the Ste. Genevieve County Detention Center.

GalaxyCon is making its debut in St. Louis October 10-12, featuring cosplay competitions, video game and tabletop game tournaments, and a marketplace with celebrity guests including Lou Ferrigno, William Shatner, Giancarlo Esposito, and St. Louis native Sean Gunn.

A man accused of shooting "blow darts" at two people in St. Louis this week is now behind bars on felony charges.

The Schafluetzel family says they’re grateful for the community’s support, as Ella will be heading to Duke this Sunday to begin her stem cell treatment.

OZARK COUNTY, Mo. - A Missouri man has been charged after admitting to illegally killing a bear in early September. According to online court dockets filed on Tuesday, Oct. 7, Curtis Hastings, born 1985, of Bakersfield, has been charged with three misdemeanors, which include importing, transporting, selling, purchasing, taking or possessing black bear/elk/parts inconsistent with [...]

A teenager faces felony charges after allegedly robbing a man at gunpoint outside of The Muny last year.

Unbeaten near the midpoint of their season, the Missouri Tigers face their toughest challenge yet: A Saturday morning showdown with the storied Alabama Crimson Tide.

The Hillsboro Hawks are in high spirits as they prepare for their big game against De Soto tonight, with FOX 2's Ty Hawkins rallying with them.

GalaxyCon has kicked off in downtown St. Louis, featuring cosplay competitions, video game and tabletop game tournaments, a marketplace, and celebrity guests including William Shatner, Giancarlo Esposito, the cast of 'K-Pop Demon Hunters', and St. Louis native Sean Gunn.

ST. LOUIS -- Saturday marks the International Day of the Girl, with celebrations and motivational events taking place across the St. Louis area this week. One such event was held at the Missouri History Museum, where middle school girls gathered for a series of empowering activities. The theme of the event was 'I Define My [...]