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More people are making appointments with their doctor's offices and urgent care locations in the St. Louis area because of the flu and other viruses that are spreading quickly this time of year.

A local organization that wants to make sure kids in need get Christmas presents this year is asking for help.

Almost an entire month since four University of Idaho students were tragically killed and police have yet to reassure this community that they are any closer to catching a suspect.

A teenager in Central Missouri who has been missing for a week could be in a neighboring county, her family says.

One of two sisters previously reported missing ins Gasconade County has been found.

A 66-year-old Hillsboro man died Saturday evening after crashing his truck along Route V in Jefferson County.

A now-former attorney for the Kansas City Police Department has released a scathing letter, calling for Interim Chief Joe Mabin to be fired.

The 1980s and 1990s mark an era of "Satanic Panic" in American history. Missouri was not immune to the panic. Satanic Panic, on the other hand, has never fully recovered.

Beginning Sunday morning, drivers who use Interstate 255 to cross the Mississippi River between Illinois and Missouri will have to take a different route.

It's the time of year for holiday light displays and a neighborhood in Webster Groves is aiming to make a difference in the lives of others.

One person has been shot Saturday evening in a St. Charles County neighborhood.

Calm start next week, rain expected soon for STL

Jim Butler Auto Group is holding its "Good Taste Campaign" fundraiser and food drive to help Missouri families in need. 

Jalen Wilson had 24 points and 10 rebounds, KJ Adams scored a career-high 19 and sixth-ranked Kansas routed Missouri 95-67 on Saturday in the Jayhawks' first visit to their old Big 12 rival in more than a decade.

The Berkeley Fire Department handed out hundreds of coats Saturday to help keep St. Louis area children warm this winter.

First-time homebuyers might have better luck in the St. Louis region than most other places around the United States, new research finds.

The Battleship Missouri Memorial has unveiled a new plaque onboard the USS Missouri to recognize the state's efforts to preserve America’s last-commissioned battleship.

Two men who were facing felony charges alleging they abused boys at a private Christian boarding school in southwest Missouri have pleaded guilty to misdemeanors, and the case against a third was dropped.

ILLINOIS (NEXSTAR) -- With the winter holidays right around the corner, drivers may see some vehicles traveling through Illinois without a front license plate attached. This may leave some travelers confused about whether that is allowed in Illinois. According to state laws, if your vehicle is registered in Illinois and you are issued two plates [...]

Four years have passed since a major wake-up call in the St. Louis Blues' only Stanley Cup title season.