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Up-and-coming medical practitioners might have better training tools with the help of Missouri School of Medicine.

While signing the income-tax-cut legislation Wednesday, Missouri Gov. Mike Parson said the estimated $760 million reduction, when fully phased in, will be “the largest tax cut in the state's history.”

The unusually low water level in the lower Mississippi River is causing barges to get stuck in mud and sand, resulting in delays for shippers, recreational boaters and even passengers on a cruise line.

The National Park Service has awarded a $500,000 grant to Tower Grove Park in an effort to refurbish four historic Victorian pavilions.

Eligible families who have not claimed the Child Tax Credit still have more time to use a simple tool to file. Officials say it helps make it easier for families to file for the funds.

Only hours away from the start of postseason, the St. Louis Cardinals complete a series of transactions to help build their roster for the Wild Card round.

ST. LOUIS COUNTY, Mo. - An endangered person advisory has been issued for a missing 12-year-old girl. Police said Dani Allen went missing Monday at 7 p.m. from her home in the 14000 block of Old Halls Ferry Road in Florissant. She is described as being 5'8" and 140 pounds, with black hair and brown [...]

Former FOX 2 reporter Mikala McGhee made the Top 16 when she took the stage Monday night in Reno, Nevada for the Miss USA pageant.

The St. Louis Cardinals have officially announced game times for this weekend's Wild Card Series, the first set of games to kick off the 2022 postseason.

Frontier Airlines celebrates new flights with low rates

We've reached the final day in the regular season careers of St. Louis Cardinals legends Albert Pujols and Yadier Molina. Many teams celebrated their careers with parting gifts.

With the enactment Wednesday of an income tax cut in Missouri, about two-thirds of U.S. states have adopted some sort of tax relief in 2022.

Missouri homicide and arson detectives are investigating the deaths of two South American researchers whose bodies were found after a weekend apartment fire near the Kansas City biomedical research center where they worked.

Coworking Cafe, a nationwide coworking space search website, recognized St. Louis as the second-best location in its "Best Cities for Remote Workers" study.

Former teacher of Rogers Middle School is arrested for the possession of child pornography.

The St. Louis Cardinals will be at full strength, for most part, when postseason begins Friday. However, there are a few situations worth monitoring in the upcoming days.

At last, the New York Yankees slugger had the American League home run record all to himself.

In the National League, it's Padres-Mets and Phillies-Cardinals. In the American League, it's Mariners-Blue Jays and Rays-Guardians.

If you look closely at the schedules for Major League Baseball's schedule for the final day of regular season, you might notice all games start within a 20-minute span of each other. It wasn't until recently, 2015 to be exact, that this became the norm.

MADISON COUNTY, Ill. - Two people were killed in a crash near Hamel, Illinois Wednesday morning. The Illinois State Police said the crash happened at approximately 7:56 a.m. at the intersection of Illinois Route 4 and Illinois Route 140. Illinois Route 4 is closed between I-55 and Illinois 143. Illinois 140 is closed at I-55. [...]