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Alzheimer's disease can rob a person of their memories, their physical independence, and eventually their lives.

St. Jude children's research hospital helps heal kids with cancer.

Pedal the Cause returns for its 13th year with a weekend of fun at the Chesterfield Mall. The weekend offers amazing food, live entertainment, and more.

Boeing agrees to pay two hundred million dollars for misleading the public about the '7-37' max.

St. Louis slugger Albert Pujols hit his 700th home run, connecting for his second drive of the game and becoming the fourth player to reach the milestone in major league history as the Cardinals routed the Los Angeles Dodgers 11-0 Friday night.

One of the hardest-hit St. Louis suburbs from July's historic flash flooding just beats out a deadline to apply for federal flood funds for buyouts.

Several festivals are planned this weekend in the St. Louis region to celebrate the first weekend of fall, including Oktoberfest and the Greater St. Louis Hispanic Festival. 

Olga and Travone Mister did not know until after their child drowned in July that summer camps in Missouri are completely unregulated.

Welcome to the 700 club, Albert Pujols! The St. Louis Cardinals legend has officially slugged his way to exclusive baseball territory in his sendoff season.

Albert is almost there! Just one home run separates Albert Pujols from one of the 700 home run club, one of the most exclusive in baseball history.

Baseball fans are staying up late Friday as the St. Louis Cardinals close in on a postseason spot. To watch it, fans will need to use an unconvential route.

We're only a few days into fall, but seasonal allergies are flaring up again.

Boeing Co. will pay $200 million to settle charges that the company and its former CEO misled investors about the safety of its 737 Max after two of the airliners crashed, killing 346 people.

Fall is a great season, if it lasts that long. All summer, we look forward to some heat and humidity relief. But sometimes fall doesn’t act like fall at all. Let's dive in.

Attorneys argued in court Friday over two lawsuits challenging a new Missouri law on voter photo identification and civic engagement rules.

Jeff Prince will cover a lot of pavement around the St. Louis area over the next few days. 

Two people face criminal charges after a St. Louis toddler died from an accidental self-inflicted gunshot wound to the head last month.

A St. Louis man accused of stealing more than $300,000 in a series of scams is behind bars in St. Charles County.

An investigation is underway after a suspected domestic situation ended with one woman dead and a home destroyed by a fire.

ILLINOIS (WCIA) -- Illinois may want to adopt Bobby McFerrin's 1988 hit "Don't Worry, Be Happy" as its new state song. The Land of Lincoln was ranked No 8. in a recent report on 2022's Happiest States in America. The story is a little different on the other side of the Mississippi River. Missouri ranks [...]