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Advocates and faith leaders rallied in east St. Louis, urging lawmakers to pass the "Clean Slate Act" to help 2.2 million eligible Illinoisans.

The Professional Women's Hockey League's takeover tour concludes with a game between Ottawa and Boston in St. Louis tomorrow, sparking speculation about a potential expansion team for the city.

Planned Parenthood Great Rivers (PPGR)—a reproductive health clinic in St. Louis—announced that it will be resuming procedural abortion care at its health center.

Debates about background checks swarmed after a newly appointed volunteer traffic commissioner was discovered to be on misdemeanor probation for leaving the scene of an accident.

ST. LOUIS -- The St. Louis region will see scattered showers late tonight through midday Saturday, with the heaviest rain expected in southern Illinois and southeast Missouri. While the metro area will be on the fringe of the system, cloudy skies and light rain will keep temperatures in the 60s. No severe weather is expected [...]

Regarding the health and safety issues at the former Famous Barr Railway Exchange Building in recent years, this acquisition was announced Friday, a move city leaders have been hopeful for. 

Dozens were trapped under the rubble after a building collapsed in the capital city of Bangkok. Rescue workers say the rubble is still too unstable to search for survivors.

Bradford pear trees, an incredibly invasive and non-native species, are back and spreading fast across Missouri.

It's an oversized inflatable way of encouraging others to get screened for cancer told by a survivor.

After a whirlwind offseason clouded by trade talks, eight-time All-Star Nolan Arenado is back for his fifth season with the St. Louis Cardinals. And he started it off with a bang, crushing a key insurance home run in Thursday's Opening Day victory.

The U.S. Health Secretary, Robert F. Kennedy Jr., agreed to visit areas affected by nuclear waste in St. Louis.

The Believe: Magic of Empowerment Gala, hosted by Variety the Children's Charity of St. Louis, will take place on Friday, May 16, 2025, at 7 p.m. at The Ritz-Carlton St. Louis, featuring Nevo Abutbul, a 13-year-old mentalist, to celebrate the limitless potential of children with disabilities.

Six Flags St. Louis will introduce a new smoke-free policy for the upcoming season, banning smoking, e-cigarettes, and vaping devices inside both its main theme park and the water park.

ST. LOUIS - Grammy-nominated artist and R&B singer Chris Brown is set to perform in St. Louis this summer as he embarks on his 30-date "Breezy Bowl XX" tour. The upcoming concert will be held at the Dome at America's Center on Friday, Sep. 5, 2025, and will also feature fellow R&B stars Bryson Tiller [...]

Missouri Gov. Mike Kehoe paid a visit to St. Louis on Thursday morning for a ceremonial signing of a sweeping crime bill that shifts control of the city's police force from local oversight to the state.

The St. Louis Battlehawks will open their new spring football season Friday evening against the Houston Roughnecks, and FOX 2 will carry the live on-air broadcast.

Emergency crews have responded to an apparent shooting Friday morning on Laclede Avenue in St. Louis' Central West End neighborhood.

A 7.7 magnitude earthquake rocked Thailand and neighboring Myanmar midday on Friday, burying an unknown number when a high-rise building under construction collapsed.

ST. LOUIS - No injuries were reported overnight Friday morning after a fire broke out at a house in west St. Louis. According to officials, the fire occurred around 1:30 a.m. on McCausland Avenue. There were no injuries reported in the fire.

Police are investigating a shooting that occurred overnight at a hotel in St. Charles, with crime scene tape seen on the inside and outside of the hotel.