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Fire crews in Warren County battled a large, three-alarm fire caused by an explosion at a warehouse in Wright City Tuesday afternoon.

A detainee has been forced to take psych medications during a 6-year pre-trial lockup.

After a 49-day-old baby died due to drug exposure in Lincoln County, six people accused of the murder pleaded not guilty.

From law enforcement to emergency responders, construction crews, and delivery drivers, essential workers are pushing through these dangerous conditions to get the job done.

A young girl died Tuesday days after being found unresponsive in a hotel swimming pool.

A St. Louis man lost his life in a head-on collision Tuesday morning.

On the coldest day of the new year, ice is the major obstacle to maneuver for everyone in the greater St. Louis area, but some souls are brave enough to face these low temperatures.

In early December, Kristie heard about the City of St. Louis’ Emergency Rental Assistance Program. The $3.3 million in federal funding is for residents struggling with past-due rent resulting from the COVID-19 pandemic.

The Major Case Squad has been activated after a woman was found shot dead in a driveway on the 1300 Block of Olive Street in Collinsville, Ill.

St. Louis's mayor, aldermen, and Greater St. Louis Inc., which promotes economic growth in the St. Louis region, praised a compromise to spend more than a quarter of a billion dollars from the 2021 $790 million legal settlement with Rams owner Enos Stan Kroenke and the NFL.

A Gold Star family from Wentzville was in Washington, D.C. for the inauguration of President Donald Trump.

Don't look now, but your Netflix bill is about to go up.

Firefighters with the North County Fire & Rescue Fire Protection District responded to a three-alarm fire late Tuesday morning at the site of an old bowling ball plant in Jennings.

Emergency crews are responding to a three-alarm fire at a commercial facility after a report of an explosion Tuesday afternoon.

A Missouri lawmaker introduced a bill that may give judges the right to finalize a divorce even if one spouse is pregnant.

A St. Louis woman appeared in federal court on Tuesday to be sentenced for stealing her late grandmother’s government benefits.

A casual conversation on a MetroLink train led police to identify and eventually arrest a suspected carjacker.

A study by Washington University School of Medicine and the VA St. Louis Health Care System has found that GLP-1 drugs can have both health benefits and risks, including reduced risks of Alzheimer's, dementia, and substance addiction, but also increase risks of pancreatitis and kidney-related conditions.

A man is offering $5,000 for information in connection to his brother's murder in 1995.

The Jefferson County Sheriff's Office announced that a man has been charged after he shot and killed another man inside his home Monday.