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Illinois Route 3 is currently closed in Sauget due to a train derailment, with crews working to clear the scene.

Salt + Smoke, a popular St. Louis-based barbecue restaurant, is set to open its first Illinois location in Edwardsville later this year.

ST. CLAIR COUNTY, Ill. - Two mobile homes were destroyed and another was left damaged after an overnight fire in Cahokia Heights Thursday morning. The fire took place around 3 a.m. on Jarvis Place. Several fire departments in the Metro East assisted in putting the fire out. No injuries were reported in the fire. The [...]

The IRS has extended the deadline for filing tax returns and making payments for individuals and businesses impacted by the tornado that struck on May 16 to November 3.

ST. LOUIS - We remain under a Heat Advisory through Thursday evening. The combination of heat and humidity makes outdoor activities difficult during the core of the day (11 a.m.-6 p.m.), and the warm, muggy nights will offer little relief. More clouds and rain chances Friday may drop up below advisory criteria, but it will [...]

ST. LOUIS (AP) — Ian Happ hit a leadoff home run and drove in three, Matthew Boyd gave up three hits in six scoreless innings and the Chicago Cubs beat the St. Louis Cardinals 8-0 on Wednesday night. Reese McGuire and Kyle Tucker also homered for the Cubs, who snapped a three-game losing streak. Boyd [...]

The entire incident was caught on camera.

Andrew Bailey initiated removal proceedings against STL Sheriff Alfred Montgomery.

A steamy night in downtown St. Louis didn’t keep City SC fans from turning out in full force.

James Blake, 23, was found guilty for the death of Kathon Moore.

In some of the city's hardest-hit areas, 67% or more of residents are uninsured or underinsured.

The FEMA centers, in collaboration with the U.S. Small Business Administration, will assist residents with disaster assistance applications at all three locations. Representatives will be available to answer questions and help tornado victims upload required documents.

BRENTWOOD, Mo. - The Animal Protective Association (APA) said its Brentwood location is facing extraordinary circumstances, as over 100 animals were brought in. “Our shelter is very full right now,” said Sarah Javier, president and CEO of the APA. “We are bursting at the seams, and for that reason, we are running an adoption special where [...]

Victims are seeking legal damages for the crash, which injured 32.

With the city making an attempt to repair, the buckle remains a safety concern.

A man has been charged with driving while intoxicated and other offenses in a deadly St. Peters motorcycle crash that killed a four-year-old boy, nearly three months since the crash.

Police responded to an accidental shooting occurred in the parking lot of the Walmart store in Shrewsbury, Missouri on Wednesday afternoon.

Zaxby's, a popular fast-casual chicken franchise, is currently exploring opportunities to expand into the St. Louis region, FOX 2 has learned.

An urgent call for help from Gateway Pet Guardians has been issued after the air conditioning on the dog and cat adoption floor has failed.

A pedestrian was struck and killed by a light-colored Mercury Mountaineer SUV with a Missouri temp tag on the rear of the vehicle, and the driver, described as a black female with a mole on the left side of her face, is being sought by police.