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Since Easter, St. Louis has experienced at least five homicides, but police say that overall murders are at an all-time low compared to last year.

A bipartisan group of lawmakers joined business leaders to express optimism over Missouri’s increasing role in the technology sector.

This time, the story takes place within the St. Louis Zoo, and animals like the sea lion are the understudies.

A Missouri woman is accused of stealing $174,000 in disability payments over 14 years, according to a new federal indictment.

For those craving the crispy deliciousness of fried chicken, food writers recently crowned one Missouri restaurant as the best in the state.

This summer, teens aged 13-17 will have the opportunity to participate in the Illinois State Police (ISP) camps.

As St. Louis native Jon Hamm stars in Apple TV+'s new hit series "Your Friends & Neighbors," the Emmy-winning actor has opened up about personal struggles that helped reshape his life, including a pivotal turn through rehab and a journey toward redemption.

Over the weekend, three separate sinkholes emerged through the City of St. Louis, damaging homes, swallowing streets, and even causing a bump, or rather a hole, in the road for the Go! St. Louis marathon this weekend.

Cape Girardeau emergency crews recovered the body of a missing Illinois man Thursday morning in the Mississippi River.

A new two-part series from "CBS Evening News" has brought renewed attention to decades-long concerns of nuclear waste contamination at Coldwater Creek and its devastating impact on St. Louis-area families.

After two decades of deadlines pushed back, the Department of Homeland Security is implementing its Real ID requirement in exactly two weeks. And more than half of Missourians are without one.

A Jefferson County man appeared in federal court Tuesday and admitted building and possessing a pipe bomb in the summer of 2023.

Shake Shack, a popular fast-casual burger chain, is preparing to open another St. Louis-area location. This time at the site of a former Fuddruckers in St. Louis County.

While in the custody of U.S. Immigration and Customs Enforcement, a man from Colombia passed away after being found unresponsive at the Phelps County Jail in Rolla.

Charges have been filed in a fatal shooting earlier this week in the Jeff-Vander-Lou neighborhood.

A Missouri middle school student and his family are suing their school district after the student was suspended for sharing a photo of a homemade art project on Snapchat. The project, made from glued-together Dr. Pepper cans, appeared to resemble a rifle.

The Major Case Squad is now investigating the death of a man in north county early Wednesday morning.

A Glasgow Village man appeared in St. Louis County Circuit Court on Monday and admitted to having inappropriate sexual contact with a pre-teen.

Sen. Dick Durbin (D-Ill.), the No. 2 Senate Democrat, announced Wednesday he will not seek reelection, capping off a decades-long Senate career. “The decision of whether to run for reelection has not been easy. I truly love the job of being United States Senator. But in my heart, I know it’s time to pass the [...]

ST. LOUIS - An overnight shooting in north St. Louis County left one person dead Wednesday morning. The shooting took place around 3:30 a.m. on the 6900 block of Greenway Avenue. An investigation into the shooting is ongoing. This is a developing story; FOX 2 will provide additional information once it comes into the newsroom.