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Nelly, a St. Louis native, will be performing live at the Cincinnati Red's Great American Ball Park on Friday as part of the Ohio Lottery Reds Post-Game Concert Series.

The Jefferson County Sheriff's Office is hopeful new DNA technology will help authorities identify the remains of a man who died 30 years ago.

We're nearing the final countdown of the 2024 St. Louis Cardinals regular season and quite possibly the final countdown of three longtime Cardinal players in St. Louis uniforms.

The East St. Louis Senior High School was placed on lockdown Wednesday morning following a threat on social media.

Each month on FOX 2, we salute local first responders, military, or veterans with our Proud to Serve award. This month, we shine the spotlight on Arnold Police Officer Joe Siebert, who can be seen around the Arnold community participating in local fundraisers throughout the year. Officer Siebert is the father of five children. Joe [...]

DES PERES, Mo. - There were no injuries after a nitrogen tank had a minor leak at West County Center on Wednesday morning. The Des Peres Fire Department responded to the scene after a security guard heard a sound coming from the tank and dialed 911. Officials say the tank was used to cool specialty [...]

Incumbent Republican U.S. Senator Josh Hawley and Democratic candidate Lucas Kunce have agreed to a live televised debate on October 31, 2024, after a contentious exchange over debate terms.

ST. LOUIS - A man was arrested after breaking into a car and firing a gunshot while at a Conoco gas station in north St. Louis County on Tuesday morning. Police say a man saw someone breaking into his car while he was inside the store on Page Avenue, just west of North and South [...]

A major crash and fire on westbound Interstate 270 near the Chain of Rocks Bridge led to a significant traffic backup, with two tractor trailers catching fire and three passenger vehicles involved, resulting in lane closures and injuries.

A 35-year-old man was arrested after using construction equipment to destroy the Angel of Harmony statue outside the Cathedral Basilica on Tuesday evening.

ST. LOUIS - A cool start out-the-door Wednesday morning as temperatures drop back into the 50s and 60s. We'll watch another nice warm-up occur Wednesday with highs approaching 90 degrees and humidity remaining low. This warm and dry pattern follows us into Thursday and Friday. A chance of rain begins to introduce itself late Thursday [...]

Getting everyone to agree on one thing is always tricky, but when it comes to the cosmos, there’s a collective sense of awe.

The Macoupin County Sheriff’s Office is investigating a death after a body was found inside a home in Sawyerville, Illinois, Tuesday evening.

Exactly seven weeks out from the November general election, FOX 2 News released the results of our exclusive, new Emerson College/The Hill/Nexstar poll.

Lance Lynn threw six strong innings in his 100th appearance at Busch Stadium, Jordan Walker homered and the St. Louis Cardinals beat the Pittsburgh Pirates 3-1. Lynn (7-4) allowed one run on four hits and struck out five. Lynn is 9-0 over his last 21 starts at Busch, where he pitched for the Cardinals from 2011-17 before rejoining St. Louis this season.

The Jenkins family fought back tears to address a judge in a St. Louis County courtroom Tuesday morning, asking the judge to increase the bond for Jonathan Jenkins’ suspected killer. 

The State of Missouri agrees 57-year-old Lisa Jackson needs special services—yet she’s not getting them.

Alderwoman Laura Keys (Ward 11) was stunned when she found 400 to 500 tires dumped in a vacant lot off North Grand Boulevard. She also discovered towering, six-foot piles of tires near O'Fallon Park.

After months of complaints regarding mail services throughout the metro, locally elected officials announced they have joined forces across party lines to combat delivery delays and find solutions to the U.S. Postal Service's growing problems

JEFFERSON CITY, Mo. (AP) — The FBI and the U.S. Postal Inspection Service on Tuesday were investigating the origin of suspicious packages that have been sent to or received by elections officials in more than 15 states, but there were no immediate reports of injuries or that any of the packages contained hazardous material. The [...]