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A new report from the Missouri Chamber of Commerce shows that the state ranks 28th in the country when it comes to manufacturing competitiveness.

Another house in danger of collapse in St. Charles County is being demolished. 

Authorities are searching for a 23-year-old man who went missing in Pike County, Missouri, nearly one week ago.

Police are investigating after a 14-year-old boy was found shot Friday at Ivory Perry Park in St. Louis.

St. Charles Police are working with Quincy Police to investigate the disappearance of Brittney D. Hoffman-Kelly, who is now considered to be dead, and are asking for public assistance in locating her remains.

ST. LOUIS - St. Louis Lambert International Airport will introduce a new restaurant from 4 Hands Brewery Co. and Peacemaker to one of its terminals in 2025. The new outpost restaurant from the brewery and seafood company is set to open in the Southwest terminal by late Jan. 2025 and will seat around 80 people. [...]

A rare, once-in-a-lifetime sighting of a yellow cardinal was captured on camera while in the backyard of a St. Louis Cardinals photographer.

A fatal crash on U.S. Route 54 in Pike County, Missouri resulted in the death of a Curryville man and serious injuries for two others, with the driver of the Lincoln not wearing a seatbelt.

A juvenile was critically injured during a shooting in the city's Visitation Park neighborhood on Friday morning.

A Webster Groves Police Department officer was injured in a crash after driving into the front porch of a home on Tuesday morning, with speeding and distracted driving ruled out as contributing factors.

A 34-year-old inmate at South Central Correctional Center in Licking, Missouri, died on Christmas Eve while serving multiple life sentences.

ST. LOUIS - Tim Ezell traveled to the Chocolate Chocolate Chocolate Company, located at 5025 Pattison Avenue. While at the location, Ezell got the opportunity to try some of the chocolate and to look at some of the new items that are set to be introduced.

ST. CLAIR COUNTY, Ill. - A fire destroyed a vacant home in Cahokia Heights Friday morning. The fire broke out around 2 a.m. Friday morning on North 72nd Street and Park Place. Neighbors told FOX 2's Nissan Rogue Runner Brian Howe that the people who lived there moved out just days ago. A house next [...]

A 32-year-old man was killed and five people were injured in a series of crashes on Interstate 70 in St. Louis County, Missouri, involving six vehicles.

Missouri State Highway Patrol Superintendent Colonel Eric Olson is set to retire in 2025, with Major Michael Turner to replace him as the 25th superintendent starting February 1.

ST. LOUIS - Our dreary weather continues Friday. Light rain in the morning will taper off to scattered showers for the afternoon. Breezy at times, lots of clouds, and highs in the low to mid 50s. A few spot showers may linger into Friday evening. Mostly cloudy, overnight temperatures fall into the mid-40s. Saturday will [...]

A judge denied bond Thursdy for one of the men charged with killing 16-year-old CBC student Colin Brown last month.

St. Louis residents began rounding up their live trees for disposal on Thursday, just 24 hours after presents were wrapped underneath them, clearing the way to prepare for spring cleaning in the new year.

For Home Sweet Home, things turned sour over the weekend.

Jason Heflin is reliving his father's death, three days after President Joe Biden commuted the death sentences of the men responsible.