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Rose Mary Weaver, 81, went missing on July 30 and is believed to be suffering from depression and has made suicidal statements to family members.

Springfield and Joplin, Missouri were ranked as the seventh and tenth cheapest places to live in the Midwest, respectively, based on cost-of-living data.

Taco Bell is planning to implement Voice AI in hundreds of U.S. drive-thru locations by the end of 2024, aiming to improve operations and enhance the customer experience.

ST. LOUIS -- Former President Donald Trump has endorsed all the leading Republican candidates in two of Missouri's major primaries. On Tuesday, Trump announced his support for both Andrew Bailey, the incumbent Attorney General, and Will Scharf, a former federal prosecutor and member of Trump’s legal team. "Missouri has two highly respected candidates running for [...]

Officials at the St. Louis County Department of Public Health have confirmed the county's first human case of West Nile virus in 2024.

The Ferguson City Council has approved the installation of 109 speed humps city-wide, funded by the American Rescue Plan Act, to slow down traffic and protect pedestrians.

One day after announcing Michael McGreevy, the Cardinals' top selection in the 2021 draft, would make his Major League debut, the club announced four additional roster moves.

A Missouri woman will spend the rest of her life in prison after admitting in federal court that she kidnapped and killed a pregnant Arkansas woman in what prosecutors say was an attempt to claim her baby. Amber Waterman of Pineville, Missouri, pleaded guilty Tuesday to one count each of kidnapping resulting in death and causing the death of a child in utero.

Chestnut Health Systems is installing vending machines in three towns in the St. Louis Metro area to provide free access to Narcan (Naloxone) for those in need, in an effort to reduce the number of opioid overdoses in the area.

Police have released video footage from the 2022 shooting at Central Visual and Performing Arts High School, showing the shooter arriving at the school, firing shots in room 323, and being fatally shot by police.

At least one person was killed and another possibly injured in a shooting outside of the DaBlitz Sports Bar and Grill in East St. Louis, Illinois, with police still investigating the incident.

Hot and very humid conditions will continue through Thursday. Top afternoon temperatures are expected to be in the upper 90s each day, with heat index values as high as 110.

The recent flooding around St. Louis left more than just humans displaced from their homes. Gateway Pet Guardians fostered out 68 dogs during the week of flooding, with more than 30 dogs being rescued from St. Clair County Animal Control after it began to severely fill with water. The weather forced the animals to swim their way out to safety.

Despite the intense heat and a touch of rain, the community’s spirit remains unbroken as vendors at the Tower Grove Park Farmer’s Market are braving the weather to keep their businesses thriving.

ST. LOUIS (AP) — Tommy Pham hit a pinch-hit grand slam in his first game back with the Cardinals and St. Louis beat the Texas Rangers 8-1 on Tuesday night. Pham’s blast off reliver Cody Bradford capped a five-run fifth. It was his first at-bat since being dealt to the Cardinals from the White Sox [...]

The state's largest university says it is eliminating its division of diversity, equity, and inclusion to be proactive and protect the $700 million in fundraising it receives from lawmakers.

Family members stood along the sidewalk in front of the Carnahan Courthouse in downtown St. Louis Tuesday night and cheered when Christopher Dunn walked outside, taking some of his first steps of freedom following a wrongful murder conviction.

ST. LOUIS -- Elliott Davis is retiring after 45 years at FOX 2. He is sharing the top ten "You Paid For It" reports. Tonight's stories include a battle with a school district that landed Elliott Davis and his photographer in jail and a chase after former Illinois Governor Rod Blagojevich. Following the reports, the [...]

A St. Peters woman partially paralyzed after being shot last month is home from the hospital.

One resident in East St. Louis says the city may be to blame for some of their flooding problems.