FOX 2 📺

A wrong-way crash on northbound I-170 near I-70 in Missouri left four people dead on Monday, highlighting the ongoing dangers on the state's roads despite new safety laws.

A vehicle struck the low-clearance bridge on Forest Park Parkway, causing significant damage.

They’re only open until the end of the month, but they’ve got their motto “Move or Die” on the door, hoping for a new chapter.

Anheuser-Busch is looking to hire workers ahead of its annual Brewery Lights holiday celebration.

A University City woman is facing a theft charge after she allegedly stole a car at a St. John gas station.

Princeville High School won $25,000 in the T-Mobile Friday Night 5G Lights competition and is now competing for the grand prize of $1 million, with the help of their new friends from Dunlap High School.

St. Louis Children’s Hospital and its physician partners at WashU Medicine are ranked among America’s Best Children’s Hospitals in the Midwest region.

Missouri's Republican attorney general is trying to get the medical records of Planned Parenthood patients who've had abortions, officials who oversee clinics in Kansas City and St. Louis said in legal filings.

ST. LOUIS - A federal jury found a leading operator of unregulated slot machines in Missouri liable for false advertising and unfair competition related to the company’s promotion of “no chance” gambling devices. The verdict, returned Monday, awarded $500,000 in damages to TNT Amusements, a supplier of traditional bar games, after the company accused Torch [...]

Scientists may have reached a breakthrough in the fight against Huntington’s disease, a rare and fatal inherited brain disorder with no cure. For the first time, a gene therapy has been shown in clinical trials to significantly slow the progression of the disease, raising cautious optimism among researchers and families.

A St. Ann woman shot overnight by a St. Louis County police officer along Interstate 70 has been charged.

The Sikeston Department of Public Safety is mourning the death of one of its officers who was killed in the line of duty.

The Webster Groves Police Department is investigating multiple reports of jewelry stolen from an apartment complex last week. At least one suspect has been arrested and charged.

A Washington County, Missouri, woman appeared in court Tuesday for a fatal shooting last week at a home she shared with the victim.

A program that provides food assistance to women, infants, and children in Missouri has made changes to its coverage, including substituting store brands for national brands and removing certain items, but the amount of food provided will remain the same.

ST. LOUIS - It's almost time again for St. Louis Blues hockey. The Blues open the 2025-26 season Thursday at home against the Minnesota Wild. It will be Jim Montgomery's first full season as head coach. The Blues are also rocking new jerseys this season that pay tribute to their storied past. On Monday, the [...]

The St. Louis Metropolitan Police Department announced that two individuals are in custody following a fatal shooting in Midtown Monday evening.

The Missouri Attorney General is moving forward with the case to remove St. Louis Sheriff Alfred Montgomery, filing a motion for a partial summary judgment Tuesday in the ongoing court case.

The City Museum in St. Louis has transformed into 'Fright at the Museum' offering Halloween-themed attractions and events now through October 26, including daily shows, skeleton performers, storytelling, two pop-up bars, and a new séance room.

Union employees in the Cahokia Unit School District have been without a new contract for 38 days as negotiations between the union and the district continue to stall, with the union opposing the district's proposal to separate the three employee groups into separate contracts and district leaders arguing that the changes are long overdue and aim to improve student outcomes.