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An elderly woman died Friday evening in a St. Charles County highway crash, according to the Missouri State Highway Patrol.

Three St. Louis companies finished among the Top 100 in Forbes’ latest list ranking America’s Best Large Employers.

Stacker compiled statistics about where people in St. Louis are looking to buy homes using data from Realtor.com.

Stacker compiled the highest paying science jobs in St. Louis, MO-IL using data from the U.S. Bureau of Labor Statistics.

A decision by the City of Jennings to hire a security guard to patrol an abandoned city-owned building is coming under fire from some citizens and council members.

Two men were caught on camera stealing a $7,500 Boy Scout trailer on Valentine's Day. Police are asking for the public's help to find them. 

The train that caused the emergency environmental disaster in Ohio is said to have come from Madison, Illinois.

The St. Louis Blues part ways with two more veterans, trading captain Ryan O'Reilly and Noel Acciari to the Toronto Maple Leafs.

Mardi Gras weekend kicks off in St. Louis on Friday night with the Mayor's Ball. It's the second year the ball is held at Union Station.

A Missouri program is trying to help pediatricians combat a growing mental health crisis. 

PARK HILLS, Mo. — When you think of your typical Airbnb, it's likely that staying in a Native American style tipi doesn't come to mind. That's because there's nothing typical about staying in a Airbnb tipi. According to the owners (and more than 500 positive reviews left by those who've experienced this unique retreat in [...]

SPRINGFIELD, Ill. (WCIA) -- Governor J.B. Pritzker has signed a bill into law that removes barriers for transgender Illinoisans looking to change the gender on their birth certificate. Previously, the Vital Records Act required a statement from a licensed health care or mental health professional in order to create a new certificate with a different [...]

Hate stairs and love horses? This converted stable in rural LaSalle County may be your perfect home.

An El Paso man allegedly smuggled a shipment of narcotics to St. Louis, where he was arrested during a traffic stop earlier this month.

Two suspects were arrested and one remains wanted after breaking into a Ladue home Friday afternoon.

A former St. Louis police officer was acquitted Friday in a rape case filed after two former colleagues said they were assaulted more than a decade ago.

Missouri Attorney General Andrew Bailey has joined 25 other states in a lawsuit challenging new federal regulations on pistols with stabilizing braces.

FOX 2 reporter Blair Ledet features stories Honoring Black History in St. Louis during this special program.

Scott Rolen, one of the most decorated third basemen of his era, will enter the National Baseball Hall of Fame with a Cardinals cap on his plaque.

Police are investigating after a teacher found a loaded gun in a five-year-old's bag at a Town & Country school.