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A two-vehicle crash on Interstate 55 is causing major backups Wednesday morning.

Starting next Monday, Illinois will be the first state to eliminate cash-bail as a condition of pretrial release.

The third Construction Career Expo is happening Wednesday.

The Gary Sinise Foundation is raising money for a Manchester Police Department veteran officer.

New details have emerged about a shooting that happened in north St. Louis County early Wednesday morning.

Some local police departments may have used a hacked computer information network.

Big changes start Wednesday at Riverview Gardens High School after multiple fights broke out on the campus Tuesday.

A 2022 NFLPA study suggests many injuries could be prevented if every NFL stadium used grass. Now, fewer than half of the NFL stadiums use grass.

A man fears his pregnant wife may give birth on the lawn of St. Louis City Hall. The couple lives there in a tent. The City of St. Louis has been allowing people to live there, as well as on city sidewalks and alleys.

The St. Louis County Police Department is looking to fill about a dozen openings in their upcoming dispatch academy that starts at the end of October.

A You Paid For It investigation discovered a big problem on a Belleville School District 118 school bus.

Police sources tell FOX 2 a computer information network they use on a regular basis is temporarily unavailable. A spokesperson for the Regional Justice Information System (REJIS) confirmed there was a security incident.

A busing boundary policy in St. Charles is forcing families to change how students get to class, but who's being allowed a school bus ride and who isn't has some parents upset.

Adam Wainwright pitched five solid innings for his 199th win, and the St. Louis Cardinals spoiled John Means' return for Baltimore, beating the Orioles 5-2 on Tuesday night.

A house fire spread to neighboring residences in University City early Tuesday evening, prompting a response from multiple departments.

The grief-stricken father of a Ladue Horton Watkins High School student killed with his two friends says his son was a good kid and he was just out having fun with his two friends when they all died.

Most Americans should get an updated COVID-19 vaccine, health officials said Tuesday. Advisers to the Centers for Disease Control and Prevention endorsed the new shots for everyone 6 months and older and the agency's director quickly signed off Tuesday on the panel's recommendation. That means doses should be available this week, some as early as [...]

More than three years after the COVID-19 pandemic landed in the United States, a new vaccine has become available.

ST. LOUIS (AP) — At least two Missouri health care centers have stopped prescribing puberty blockers and hormones to minors for the purpose of gender transition, citing a new state law that one clinic says “creates unsustainable liability” for health care workers. Washington University Transgender Center at St. Louis Children's Hospital on Monday announced it [...]

Broniec is current chief judge of the state appeals court based in St. Louis. She will replace George W. Draper III, a Democratic appointee who is retiring.