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A local harm reduction group has confirmed that a new antidote-resistant drug called "Benzo Dope" has been found in central Illinois.

ST. LOUIS COUNTY, Mo. - A man pleaded guilty Monday to shooting a Maryland Heights police officer in June 2019. Menius Ellis, 20, pleaded guilty to two counts of first-degree assault or attempt, serious physical injury or special victim, two counts of armed criminal action, and stealing an item of $150 in value or less [...]

St. Louis County Prosecuting Attorney Wesley Bell joined several dozen elected prosecutors from around the country in signing a letter vowing not to prosecute or enforce abortion bans in the wake of the United States Supreme Court's decision to overturn Roe v. Wade.

Three people have died and at least 50 injured after an Amtrak Southwest Chief train hit a dump truck at a public crossing and derailed.

The primaries will also offer new insight about the state of the Republican Party, with the central issue in virtually every GOP contest being fealty to Trump and his baseless conspiracy theories.

ST. LOUIS - Ameren Missouri is working to acquire a new solar power site that is 25 times larger than any other in the state. Ameren Missouri will acquire the facility, Huck Finn Solar Project, "pursuant to a build-transfer agreement with EDF Renewables, a company with a longstanding track record of developing and building renewable [...]

ST. LOUIS - A 22-year-old man was shot in the face Sunday afternoon in St. Louis' Gravois Park neighborhood. Police said officers found Theoreon Sanders at approximately 5:50 p.m. inside a residence suffering from a gunshot wound. He was pronounced dead at the scene. It is unknown at this time what led up to the [...]

This home may have the backyard and basement of your dreams!

WASHINGTON, Mo. - A Washington, Missouri man who once weighed 540 pounds is now down to 270. Jeff Brinker, 57, sells industrial automation equipment and has traveled on a company expense account for 30 years. "So I could always eat whatever I wanted to eat. So now it's become about eating to survive as opposed [...]

The trial of a St. Louis County man accused of killing his 9-year-old disabled son began with a contentious day in court, marked by numerous objections and visits to the bench by prosecutors and defense attorneys.

Grammy Award winner Michael Buble is coming to St. Louis.

The Florissant Police Department reported that three people were killed in a crash Monday morning.

St. Louis residents have flooded FOX 2 with calls and emails complaining about a lack of service they pay for.

Runners and walkers gathered in St. Charles County on Sunday morning to exercise and raise money and support for people in need during the fifth annual Wentzville Blue Line Family 5K run/walk event.

Bobby Ray Davis was last seen Sunday morning at his family's home near Musick Avenue and Gravois Road.

When a 16-year-old was shot and killed early Sunday morning, Jefferson County sheriff’s deputies were initially told it happened while the victim was driving. Investigators later uncovered a different story, which took them to another teen as the suspect.

Police are investigating a series of car break-ins at the FedEx distribution center in Overland over the weekend. Dozens of cars were targeted while employees were on the clock.

A baby alligator is on the lam in south St. Louis.

WAUCONDA, Ill. — The race to be Illinois' next governor is also a battle among billionaires, including two whose names won't appear on Tuesday's primary ballot. Republican candidates Darren Bailey, who as a state lawmaker fought pandemic measures such as mask mandates, and former prosecutor Richard Irvin, the first Black mayor of Chicago's largest suburb, [...]