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The man accused of killing a St. Louis police officer in a drunk driving crash on Interstate 70 last year will appear in court on Monday morning to presumably plead guilty.

Blinatumomab, a new drug for childhood leukemia, has been a game-changer for young patients, allowing them to live more normal lives while undergoing treatment.

A new campaign urging drivers to slow down is taking its message to dangerous streets across the St. Louis region.

An 18-year-old from St. Charles is facing serious accusations after he was charged for allegedly robbing a DoorDash driver.

An estimated 10.5% of Missourians receive some sort of SNAP subsidy. But if the government remains closed, states like Missouri have no other choice than to stop payments. Although it's administered through states, SNAP funding is 100% federal funding.

The union representing Boeing machinists has changed course and will allow members to vote on a new contract.

A man with ties to St. Louis is among 34 people charged in connection with wide-ranging FBI investigations into illegal sports betting and rigged poker games.

Four members of gubernatorial candidate Darren Bailey's family died in a helicopter crash in Montana Wednesday night. 

Stunning findings by police are providing some answers in that massive north St. Louis County explosion that leveled an entire block.

An Edwardsville, Illinois, man pleaded guilty and was sentenced Wednesday for being a child predator.

Nearly 56,000 federal employees in Missouri will not receive scheduled paychecks this Friday as the federal government shutdown stretches beyond three weeks.

If you're looking to bring a piece of the theatre home with you, The Muny's first garage sale in almost 10 years may have it.

ST. CHARLES, Mo. — On Monday, the city of St. Charles approved plans for a new apartment complex that will add more than 200 apartments near Highway 364. ARCO Construction submitted the application on behalf of Porterhouse Development LLC. They’re calling the future area the Boulders at Southpointe Apartments. It’ll be a multi-family development along [...]

A three-year-old child was injured in an apparent shooting Thursday afternoon in St. Louis' Wells-Goodfellow neighborhood.

On Oct. 16, the Jefferson County Health Department announced a positive case of West Nile virus.

An electrical contractor has filed a mechanic’s lien claiming that they are owed over $800,000 for work on a Barnes-Jewish Hospital construction project. 

A Florissant man appeared in court Thursday morning for his role in an armed carjacking at the start of the year.

Cable giant Charter Communications is laying off 1,200 employees nationwide, including some employees in St. Louis, according to several reports.

The Support Our Farmers and Ranchers Act of 2025 would deliver direct payments for farmers and ranchers using revenue collected from President Donald Trump’s tariffs.

On Monday, Michael Winston, 29, was sentenced to 15 years in prison for the shooting death of Michelle Sobel.