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Inside the SSM SLUCare Toxicology Laboratory, Dr. Sarah Riley is testing everything from potato chips to candy. It’s part of an effort to keep the community safe in a program called Project Eagle Fang.

A Waukegan, Illinois, man appeared in federal court Monday and admitted traveling outside state lines with the intent to open multiple fraudulent bank accounts to deposit checks stolen from the mail.

Missouri’s only nuclear reactor is back online following an issue with the plant's water system that forced a shutdown last month.

An O’Fallon, Illinois, woman realized a dream four decades in the making, inside one of the most iconic homes in the world.

The City of St. Louis is spending millions on vacant buildings, and fire response during the winter plays a role in that number.

A father remains at large after officials accuse him of his alleged involvement in the death of his 3-month-old son.

A Missouri lawmaker is looking to end Missouri’s death penalty under a new bill filed in the House. The legislation would repeal more than two dozen regulations that enable capital punishment and replace them with language that removes the death penalty as a sentencing option.

The man accused of seriously wounding a Granite City police officer last week was charged Monday and could face up to 100 years in Illinois prison if convicted of those charges.

The 2026 Mayor’s Ball will return to St. Louis City Hall.  Mayor Cara Spencer and the Mardi Gras Foundation made the announcement regarding one of the city’s most celebrated events.

On Sunday, the St. Louis Film Critics Association (STLFCA) announced its 2025 award nominees across 26 categories, from the prototypical Best Actor and Best Director to more niche categories like Best Scene and Best Stunts.

Next year, the Muny will start the process of upgrading and renovating their auditorium.

The Missouri Department of Conservation (MDC) is calling on the people to help with the upcoming Christmas bird count. They're encouraging any experienced birdwatchers in the state to become "citizen scientists" and help out with the National Audubon Society’s 2025 Christmas Bird Count.

A Jefferson County judge signed an arrest warrant for a St. Louis County man accused of stealing a motorized shopping cart from a grocery store.

Hayden K. Stover, 17, and Tashika Stover, 40, both died of smoke inhalation due to a fire at 1205 Eastholme Avenue in Bloomington on November 26, and the circumstances surrounding the incident remain under investigation.

Charges have been filed after a man was caught with a stolen wallet at a Little Caesar's over the weekend.

A St. Louis man appeared in court Monday afternoon for committing an armed robbery the same day he pleaded guilty to a different robbery.

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Spire Missouri is launching a new program to waive its $22 monthly customer charge for qualified low-income customers starting next year

Monday marks 20 years since St. Louis bid farewell to Busch Memorial Stadium. Specifically, the final day of demolition to make way for the St. Louis Cardinals' current home, Busch Stadium III.

ST. LOUIS — It's a cold start Monday morning with clouds still in place overhead. Clouds should gradually decrease Monday but temperatures will stay in the low to mid-30s. Temperatures swing upward for Tuesday with highs climbing into the 50s. Two cold fronts come through Tuesday night through Friday. The first cold front will bring [...]