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A woman was killed and a man was injured in a crash involving a Chevrolet Trailblazer and a Saturn Ion in Wentzville, Missouri, on Monday afternoon, with both drivers not wearing seatbelts at the time of the crash.

St. Louis native and beloved actor John Goodman walked the red carpet for the Hollywood premiere of the new "Smurfs" movie over the weekend, where his ongoing weight-loss transformation drew fresh attention.

A Jefferson County man, a Wildwood man, and a Chesterfield woman are accused of stealing more than $25,000 in equipment and other property from the St. Louis County Parks Department and Lou Fusz Soccer Fields last summer.

Two individuals are in custody after a shooting that left one woman injured early Tuesday morning.

The St. Louis Cardinals have had their share of surprise All-Stars over the years, players that might not by top of mind when fans think back. And in some years, they weren't even the team's only selection.

Missouri Gov. Mike Kehoe signed an array of bills last week, including one that will affect the way temporary tags are issued and time limits beginning next month.

The new USDA Midwestern Food Safety Lab in Normandy will enhance food safety efforts in the region, provide jobs for local students, and help ensure the nation's meat, poultry, and processed egg supply is safe and properly labeled.

St. Louis Public Schools approved a revised plan to relocate over 2,000 students from seven damaged schools affected by the May 16 tornado, with teachers having their own classrooms and schools maintaining separate staff.

ST. LOUIS - A warm and muggy start Tuesday with some spots of fog possible early. Tuesday will be partly cloudy, with scattered showers and storms expected in the afternoon. Temperature highs are expected to reach the upper 80s. The chance for rain will extend farther north Tuesday as the stalled front over the area [...]

ST. LOUIS – City SC caretaker manager David Critchley walked into the post-match press conference room with a smile and his head held high, securing his second MLS win.   “That felt good,” Critchley said with a smile. City, for the first time this season, came back to win a game after trailing at halftime. [...]

The city of St. Louis hosted a workshop Monday night to collect the public's input on a proposed Bike Network, which is part of the TMP, Transportation and Mobility Plan.

For Skip Kernan, 65, it wasn’t a hike in the woods that led to a medical emergency. It was a day on the golf course.

So far, officials have taken in four raccoons.

Missouri's Task Force One has deployed 35 additional members.

Missouri Governor Mike Kehoe signed 11 more bills into law Monday, ranging from public safety to real estate to agriculture.

HB 754 established Missouri's Electronic Wills and Electronic Estate Planning Documents Act.

A day later, the scene at St. Louis Lambert International Airport has changed, with passengers easily dropping off and checking in. But just 24 hours earlier – long lines outside the terminals.

Officials have charged a man in connection to a fatal shooting outside a bar in Alton, Illinois.

A small community in north St. Louis County now has a full-time police force.

PEORIA, Ill. (WMBD) -- A Drinking Water Notice was issued Monday Illinois American Water Co., for the entire city of Peoria after 14 of 103 water samples exceeded "action level" lead quantities. While legally, a notice to the entire community was required as more than 10% of the samples exceeded safe lead levels, the company [...]